Genetic Causes of Inner Ear Anomalies: a Review from the Turkish Study Group for Inner Ear Anomalies

Emre Ocak, Duygu Duman, Mustafa Tekin

Research output: Contribution to journalArticle

Abstract

Inner ear anomalies diagnosed using a radiological study are detected in almost 30% of cases with congenital or prelingual-onset sensorineural hearing loss. Inner ear anomalies can be isolated or occur along with a part of a syndrome involving other systems. Although astonishing progress has been made in research aimed at revealing the genetic causes of hearing loss in the past few decades, only a few genes have been linked to inner ear anomalies. The aim of this review is to discuss the known genetic causes of inner ear anomalies. Identifying the genetic causes of inner ear anomalies is important for guiding clinical care that includes empowered reproductive decisions provided to the affected individuals. Furthermore, understanding the molecular underpinnings of the development of the inner ear in humans is important to develop novel treatment strategies for people with hearing loss.

Original languageEnglish (US)
Pages (from-to)206-211
Number of pages6
JournalBalkan medical journal
Volume36
Issue number4
DOIs
StatePublished - Jul 11 2019
Externally publishedYes

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Inner Ear
Hearing Loss
Sensorineural Hearing Loss
Research
Genes

Keywords

  • Anomaly
  • genetics
  • inner ear
  • syndrome

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Genetic Causes of Inner Ear Anomalies : a Review from the Turkish Study Group for Inner Ear Anomalies. / Ocak, Emre; Duman, Duygu; Tekin, Mustafa.

In: Balkan medical journal, Vol. 36, No. 4, 11.07.2019, p. 206-211.

Research output: Contribution to journalArticle

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