Abstract
Over the last decade there has been great interest in generating populations of antigen presenting cells (APC), which can be exploited to improve immune responses to a variety of diseases including malignancies. Dendritic cells (DC) are an APC population that are easily generated ex vivo using a variety of cytokines. Cytokines can also be used to further manipulate these cells in maturation and function. The following discussion will provide an overview of dendritic cell isolation and generation with a focus on the role cytokines play in this process.
| Original language | English |
|---|---|
| Pages (from-to) | 117-124 |
| Number of pages | 8 |
| Journal | Transfusion and Apheresis Science |
| Volume | 24 |
| Issue number | 2 |
| DOIs | |
| State | Published - Nov 28 2001 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Hematology
- Infectious Diseases
Cite this
Generation of dendritic cells : Role of cytokines and potential clinical applications. / Syme, Rachel; Glück, Stefan.
In: Transfusion and Apheresis Science, Vol. 24, No. 2, 28.11.2001, p. 117-124.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Generation of dendritic cells
T2 - Role of cytokines and potential clinical applications
AU - Syme, Rachel
AU - Glück, Stefan
PY - 2001/11/28
Y1 - 2001/11/28
N2 - Over the last decade there has been great interest in generating populations of antigen presenting cells (APC), which can be exploited to improve immune responses to a variety of diseases including malignancies. Dendritic cells (DC) are an APC population that are easily generated ex vivo using a variety of cytokines. Cytokines can also be used to further manipulate these cells in maturation and function. The following discussion will provide an overview of dendritic cell isolation and generation with a focus on the role cytokines play in this process.
AB - Over the last decade there has been great interest in generating populations of antigen presenting cells (APC), which can be exploited to improve immune responses to a variety of diseases including malignancies. Dendritic cells (DC) are an APC population that are easily generated ex vivo using a variety of cytokines. Cytokines can also be used to further manipulate these cells in maturation and function. The following discussion will provide an overview of dendritic cell isolation and generation with a focus on the role cytokines play in this process.
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UR - http://www.scopus.com/inward/citedby.url?scp=0035165666&partnerID=8YFLogxK
U2 - 10.1016/S1473-0502(01)00005-2
DO - 10.1016/S1473-0502(01)00005-2
M3 - Article
VL - 24
SP - 117
EP - 124
JO - Transfusion and Apheresis Science
JF - Transfusion and Apheresis Science
SN - 1473-0502
IS - 2
ER -