Generation of dendritic cells

Role of cytokines and potential clinical applications

Rachel Syme, Stefan Glück

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Over the last decade there has been great interest in generating populations of antigen presenting cells (APC), which can be exploited to improve immune responses to a variety of diseases including malignancies. Dendritic cells (DC) are an APC population that are easily generated ex vivo using a variety of cytokines. Cytokines can also be used to further manipulate these cells in maturation and function. The following discussion will provide an overview of dendritic cell isolation and generation with a focus on the role cytokines play in this process.

Original languageEnglish
Pages (from-to)117-124
Number of pages8
JournalTransfusion and Apheresis Science
Volume24
Issue number2
DOIs
StatePublished - Nov 28 2001
Externally publishedYes

Fingerprint

Dendritic Cells
Antigen-Presenting Cells
Cytokines
Cell Separation
Population
Neoplasms

ASJC Scopus subject areas

  • Hematology
  • Infectious Diseases

Cite this

Generation of dendritic cells : Role of cytokines and potential clinical applications. / Syme, Rachel; Glück, Stefan.

In: Transfusion and Apheresis Science, Vol. 24, No. 2, 28.11.2001, p. 117-124.

Research output: Contribution to journalArticle

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