General vs local anesthesia for the percutaneous laser treatment of twin-twin transfusion syndrome

A. Cristina Rossi, Marc A. Kaufman, Patricia W. Bornick, Rubén A. Quintero

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


Objective: The purpose of this study was to review our anesthetic experience in selective laser photocoagulation of communicating vessels (SLPCV) to treat twin-twin transfusion syndrome (TTTS). Study Design: A total of 266 consecutive eligible patients were studied. Twenty-seven patients (10%) underwent general anesthesia (GenA), 100 (38%) received total intravenous anesthesia (TIVA), and 139 (52%) received local anesthesia/conscious sedation (LocA). Maternal-fetal hemodynamic fluctuations were compared between groups. Results: Maternal blood pressure decreased significantly in all 3 groups during surgery (P < .0001) but was more evident in the GenA and TIVA groups (P < .0001). Maternal heart rate varied significantly in GenA (P = .02) but was constant in LocA and TIVA. There were no significant differences in fetal heart rate changes between the groups. Intraamniotic bleeding occurred more frequently with GenA and TIVA than LocA(P < .0001). Conclusion: Local anesthesia is the safest anesthetic technique for SLPCV in TTTS patients.

Original languageEnglish (US)
Pages (from-to)137.e1-137.e7
JournalAmerican journal of obstetrics and gynecology
Issue number2
StatePublished - Aug 2008


  • fetal outcome
  • general anesthesia
  • local anesthesia/conscious sedation
  • maternal outcome
  • twin-twin transfusion syndrome

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology


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