Both genetic and epigenetic events play an important role in oncogenic processes. This review discusses the four hypothesis for the origin of neoplastic transformation (mutational genetic, nonmutational genetic, viral, and epigenetic) in the context of a summary of our current knowledge of the pathobiology of cancer.
|Original language||English (US)|
|Number of pages||99|
|Journal||Critical reviews in oncogenesis|
|State||Published - 1998|
- Tumor suppressor genes
ASJC Scopus subject areas
- Cancer Research