TY - JOUR
T1 - General anesthesia in the pediatric population
AU - Cavuoto, Kara M.
AU - Rodriguez, Luis Ignacio
AU - Tutiven, Jacqueline
AU - Chang, Ta C.
PY - 2014/9
Y1 - 2014/9
N2 - Purpose of Review: This article reviews the pertinent perioperative, intraoperative, and short- and long-term postoperative risks associated with general anesthesia in children undergoing ocular surgery. Recent Findings: Animal studies suggest an association between general anesthesia and neurodevelopmental delay; however, animal pharmacodynamics and pharmacokinetics do not directly correlate with human metrics. Retrospective human studies present conflicting data. Further, prospective studies in humans are underway, with projected results available within the next 3-5 years. Summary: All surgeons should be aware of current practices in pediatric anesthetic care, as well as the immediate- and long-term risks of general anesthesia. Ophthalmologists with pediatric patients should be aware of the potentially life-threatening conditions associated with general anesthesia. Additionally, the relative lifelong risks and benefits of general anesthetic exposure should be considered when recommending surgery, especially in light of the child's age, health status, and necessity of multiple anesthetic events.
AB - Purpose of Review: This article reviews the pertinent perioperative, intraoperative, and short- and long-term postoperative risks associated with general anesthesia in children undergoing ocular surgery. Recent Findings: Animal studies suggest an association between general anesthesia and neurodevelopmental delay; however, animal pharmacodynamics and pharmacokinetics do not directly correlate with human metrics. Retrospective human studies present conflicting data. Further, prospective studies in humans are underway, with projected results available within the next 3-5 years. Summary: All surgeons should be aware of current practices in pediatric anesthetic care, as well as the immediate- and long-term risks of general anesthesia. Ophthalmologists with pediatric patients should be aware of the potentially life-threatening conditions associated with general anesthesia. Additionally, the relative lifelong risks and benefits of general anesthetic exposure should be considered when recommending surgery, especially in light of the child's age, health status, and necessity of multiple anesthetic events.
KW - general anesthesia
KW - neurodevelopmental delay
KW - pediatric ocular surgery
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U2 - 10.1097/ICU.0000000000000088
DO - 10.1097/ICU.0000000000000088
M3 - Review article
C2 - 24991869
AN - SCOPUS:84906101410
VL - 25
SP - 411
EP - 416
JO - Current Opinion in Ophthalmology
JF - Current Opinion in Ophthalmology
SN - 1040-8738
IS - 5
ER -