Gene therapy for inherited disorders

Rita H. Pickler, Cindy Munro

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

With an increase in understanding of the role of genes in disease pathogenesis, gene therapy has become a reality for some disorders and an increased possibility for many others. One type of gene therapy requires only gene addition for treatment. Different methods for gene addition are being tested, based on the cell typology necessary to make the therapy effective. Gene therapy trials for patients with adenosine deaminase deficiency involve a retroviral approach. Gene therapy trials for patients with cystic fibrosis involve an adenoviral approach. This article describes the differences between these two methods of gene therapy. The application of this knowledge to pediatric nursing practice is discussed.

Original languageEnglish (US)
Pages (from-to)40-47
Number of pages8
JournalJournal of Pediatric Nursing
Volume10
Issue number1
DOIs
StatePublished - Jan 1 1995
Externally publishedYes

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Genetic Therapy
Pediatric Nursing
Genes
Cystic Fibrosis
Therapeutics

ASJC Scopus subject areas

  • Pediatrics

Cite this

Gene therapy for inherited disorders. / Pickler, Rita H.; Munro, Cindy.

In: Journal of Pediatric Nursing, Vol. 10, No. 1, 01.01.1995, p. 40-47.

Research output: Contribution to journalArticle

Pickler, Rita H. ; Munro, Cindy. / Gene therapy for inherited disorders. In: Journal of Pediatric Nursing. 1995 ; Vol. 10, No. 1. pp. 40-47.
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