Gene therapy

E. V. Badiavas, V. Falanga

Research output: Contribution to journalReview article

7 Scopus citations

Abstract

With recent advances in molecular biology, the ability to transfer genes to patients is becoming a reality. Ongoing clinical trials using gene transfer techniques have illustrated the potential and pitfalls of this new therapeutic modality for the treatment of a wide variety of disorders. While these techniques are not currently a part of routine clinical practice, it is only a matter of time until some form of gene therapy is approved for general use in the clinic. This review highlights some of the basic methods used in current gene therapy protocols. The objective of this review is to familiarize practitioners with these concepts so they can more effectively follow the progress of this emerging technology and better inform their patients.

Original languageEnglish (US)
Pages (from-to)175-192
Number of pages18
JournalJournal of Dermatology
Volume28
Issue number4
DOIs
StatePublished - Jan 1 2001

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Keywords

  • Gene therapy
  • Gene transfer
  • Transduction
  • Transfection

ASJC Scopus subject areas

  • Dermatology

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