Gender susceptibility to mycobacterial infections in patients with non-CF bronchiectasis

Mehdi Mirsaeidi, Ruxana T. Sadikot

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

Non-tuberculous mycobacteria (NTM) are environmental microbes that cause a variety of diseases both in immunocompromised and immunocompetent patients. Epidemiologic data indicate that there has been a global rise in the incidence of NTM infections. It has also been noted that NTM infections have a predilection to occur in postmenopausal women. In a recent study, it was demonstrated that in patients with non-CF bronchiectasis the probability of NTM isolation was significantly higher in elderly female patients and in those with a low body mass index. However, the mechanisms of causality of these gender differences and morpho-phenotypes remain enigmatic. The present study reviews the data and plausible mechanisms which might provide clues to this gender susceptibility and morpho-phenotypes of patients with bronchiectasis and NTM.

Original languageEnglish (US)
Pages (from-to)92-96
Number of pages5
JournalInternational Journal of Mycobacteriology
Volume4
Issue number2
DOIs
StatePublished - Jun 1 2015
Externally publishedYes

Keywords

  • Bronchiectasis
  • Gender
  • Nontuberculous mycobacteria
  • Woman

ASJC Scopus subject areas

  • Infectious Diseases
  • Microbiology (medical)

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