Gender disparities in ocular inflammatory disorders

Hatice Nida Sen, Janet Davis, Didar Ucar, Austin Fox, Chi Chao Chan, Debra A. Goldstein

Research output: Contribution to journalReview article

6 Scopus citations

Abstract

Ocular inflammatory disorders disproportionately affect women, and the majority of affected women are of childbearing age. The role of sex or reproductive hormones has been proposed in many other inflammatory or autoimmune disorders, and findings from non-ocular autoimmune diseases suggest a complex interaction between sex hormones, genetic factors and the immune system. However, despite the age and sex bias, factors that influence this disparity are complicated and unclear. This review aims to evaluate the gender disparities in prevalence, incidence and severity of the most common infectious and non-infectious ocular inflammatory disorders.

Original languageEnglish (US)
Pages (from-to)146-161
Number of pages16
JournalCurrent Eye Research
Volume40
Issue number2
DOIs
StatePublished - Feb 1 2015

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Keywords

  • Disparity
  • Gender
  • Ocular inflammation
  • Sex
  • Uveitis

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Cite this

Sen, H. N., Davis, J., Ucar, D., Fox, A., Chan, C. C., & Goldstein, D. A. (2015). Gender disparities in ocular inflammatory disorders. Current Eye Research, 40(2), 146-161. https://doi.org/10.3109/02713683.2014.932388