GEMCITABINE-INDUCED RETINOPATHY

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

PURPOSE: To report a case of Purtscher-like retinopathy associated with gemcitabine.

METHODS: The author reports a 68-year-old woman who presented with a 4-month history of bilateral vision loss. She had a history of diabetes, hypertension, and leiomyosarcoma, diagnosed 5 months before presentation and had completed 5 cycles of combination treatment with gemcitabine and docetaxel. Clinical examination revealed a Purtscher-like retinopathy that improved after gemcitabine cessation without the development of cystoid macular edema or retinal neovascularization.

CONCLUSION: This case highlights the importance of recognizing gemcitabine-induced ischemic retinopathy that can be associated with life-threatening myocardial or renal ischemia.

Original languageEnglish (US)
Pages (from-to)240-241
Number of pages2
JournalRetinal cases & brief reports
Volume12
Issue number3
DOIs
StatePublished - Jun 1 2018

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gemcitabine
docetaxel
Retinal Neovascularization
Macular Edema
Leiomyosarcoma
Ischemia
Hypertension
Kidney

ASJC Scopus subject areas

  • Medicine(all)

Cite this

GEMCITABINE-INDUCED RETINOPATHY. / Kovach, Jaclyn.

In: Retinal cases & brief reports, Vol. 12, No. 3, 01.06.2018, p. 240-241.

Research output: Contribution to journalArticle

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AB - PURPOSE: To report a case of Purtscher-like retinopathy associated with gemcitabine.METHODS: The author reports a 68-year-old woman who presented with a 4-month history of bilateral vision loss. She had a history of diabetes, hypertension, and leiomyosarcoma, diagnosed 5 months before presentation and had completed 5 cycles of combination treatment with gemcitabine and docetaxel. Clinical examination revealed a Purtscher-like retinopathy that improved after gemcitabine cessation without the development of cystoid macular edema or retinal neovascularization.CONCLUSION: This case highlights the importance of recognizing gemcitabine-induced ischemic retinopathy that can be associated with life-threatening myocardial or renal ischemia.

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