Gel filtration of posterior pituitary hormones

Jerker Porath, Andrew V. Schally

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

Mixtures of posterior pituitary hormones were fractionated by filtration through Sephadex gel columns. Several solvent systems and column materials are given for a successful separation of lysine vasopressin from a-MSH and of The latter from α-MSH. Oxytocin, partially purified by chromatography on carboxymethyl cellulose, can be obtained in a high state of purity by molecular sieving on dextran gels. The technique described is fast and simple and can be used with very small or very large quantities of material.

Original languageEnglish (US)
Pages (from-to)738-742
Number of pages5
JournalEndocrinology
Volume70
Issue number5
DOIs
StatePublished - May 1962
Externally publishedYes

ASJC Scopus subject areas

  • Endocrinology

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