Gastroparesis: Current diagnostic challenges and management considerations

Shamaila Waseem, Baharak Moshiree, Peter V. Draganov

Research output: Contribution to journalArticle

82 Citations (Scopus)

Abstract

Gastroparesis refers to abnormal gastric motility characterized by delayed gastric emptying in the absence of mechanical obstruction. The most common etiologies include diabetes, post-surgical and idiopathic. The most common symptoms are nausea, vomiting and epigastric pain. Gastroparesis is estimated to affect 4% of the population and symptomatology may range from little effect on daily activity to severe disability and frequent hospitalizations. The gold standard of diagnosis is solid meal gastric scintigraphy. Treatment is multimodal and includes dietary modification, prokinetic and anti-emetic medications, and surgical interventions. New advances in drug therapy, and gastric electrical stimulation techniques have been introduced and might provide new hope to patients with refractory gastroparesis. In this comprehensive review, we discuss gastroparesis with emphasis on the latest developments; from the perspective of the practicing clinician.

Original languageEnglish
Pages (from-to)25-37
Number of pages13
JournalWorld Journal of Gastroenterology
Volume15
Issue number1
DOIs
StatePublished - Jan 7 2009
Externally publishedYes

Fingerprint

Gastroparesis
Stomach
Diet Therapy
Combined Modality Therapy
Antiemetics
Gastric Emptying
Radionuclide Imaging
Nausea
Electric Stimulation
Vomiting
Meals
Hospitalization
Drug Therapy
Pain
Population

Keywords

  • Gastroparesis
  • Nausea
  • Prokinetic
  • Therapy
  • Vomiting

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Gastroparesis : Current diagnostic challenges and management considerations. / Waseem, Shamaila; Moshiree, Baharak; Draganov, Peter V.

In: World Journal of Gastroenterology, Vol. 15, No. 1, 07.01.2009, p. 25-37.

Research output: Contribution to journalArticle

Waseem, Shamaila ; Moshiree, Baharak ; Draganov, Peter V. / Gastroparesis : Current diagnostic challenges and management considerations. In: World Journal of Gastroenterology. 2009 ; Vol. 15, No. 1. pp. 25-37.
@article{5d955798239d46f7bac82c0c5ccbb5f4,
title = "Gastroparesis: Current diagnostic challenges and management considerations",
abstract = "Gastroparesis refers to abnormal gastric motility characterized by delayed gastric emptying in the absence of mechanical obstruction. The most common etiologies include diabetes, post-surgical and idiopathic. The most common symptoms are nausea, vomiting and epigastric pain. Gastroparesis is estimated to affect 4{\%} of the population and symptomatology may range from little effect on daily activity to severe disability and frequent hospitalizations. The gold standard of diagnosis is solid meal gastric scintigraphy. Treatment is multimodal and includes dietary modification, prokinetic and anti-emetic medications, and surgical interventions. New advances in drug therapy, and gastric electrical stimulation techniques have been introduced and might provide new hope to patients with refractory gastroparesis. In this comprehensive review, we discuss gastroparesis with emphasis on the latest developments; from the perspective of the practicing clinician.",
keywords = "Gastroparesis, Nausea, Prokinetic, Therapy, Vomiting",
author = "Shamaila Waseem and Baharak Moshiree and Draganov, {Peter V.}",
year = "2009",
month = "1",
day = "7",
doi = "10.3748/wjg.15.25",
language = "English",
volume = "15",
pages = "25--37",
journal = "World Journal of Gastroenterology",
issn = "1007-9327",
publisher = "WJG Press",
number = "1",

}

TY - JOUR

T1 - Gastroparesis

T2 - Current diagnostic challenges and management considerations

AU - Waseem, Shamaila

AU - Moshiree, Baharak

AU - Draganov, Peter V.

PY - 2009/1/7

Y1 - 2009/1/7

N2 - Gastroparesis refers to abnormal gastric motility characterized by delayed gastric emptying in the absence of mechanical obstruction. The most common etiologies include diabetes, post-surgical and idiopathic. The most common symptoms are nausea, vomiting and epigastric pain. Gastroparesis is estimated to affect 4% of the population and symptomatology may range from little effect on daily activity to severe disability and frequent hospitalizations. The gold standard of diagnosis is solid meal gastric scintigraphy. Treatment is multimodal and includes dietary modification, prokinetic and anti-emetic medications, and surgical interventions. New advances in drug therapy, and gastric electrical stimulation techniques have been introduced and might provide new hope to patients with refractory gastroparesis. In this comprehensive review, we discuss gastroparesis with emphasis on the latest developments; from the perspective of the practicing clinician.

AB - Gastroparesis refers to abnormal gastric motility characterized by delayed gastric emptying in the absence of mechanical obstruction. The most common etiologies include diabetes, post-surgical and idiopathic. The most common symptoms are nausea, vomiting and epigastric pain. Gastroparesis is estimated to affect 4% of the population and symptomatology may range from little effect on daily activity to severe disability and frequent hospitalizations. The gold standard of diagnosis is solid meal gastric scintigraphy. Treatment is multimodal and includes dietary modification, prokinetic and anti-emetic medications, and surgical interventions. New advances in drug therapy, and gastric electrical stimulation techniques have been introduced and might provide new hope to patients with refractory gastroparesis. In this comprehensive review, we discuss gastroparesis with emphasis on the latest developments; from the perspective of the practicing clinician.

KW - Gastroparesis

KW - Nausea

KW - Prokinetic

KW - Therapy

KW - Vomiting

UR - http://www.scopus.com/inward/record.url?scp=59249108065&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=59249108065&partnerID=8YFLogxK

U2 - 10.3748/wjg.15.25

DO - 10.3748/wjg.15.25

M3 - Article

C2 - 19115465

AN - SCOPUS:59249108065

VL - 15

SP - 25

EP - 37

JO - World Journal of Gastroenterology

JF - World Journal of Gastroenterology

SN - 1007-9327

IS - 1

ER -