Gastrointestinal and Hepatic Disease in Fibromyalgia

Richard A. Schatz, Baharak Moshiree

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

Fibromyalgia (FM) has historically been associated with several diseases in gastroenterology and hepatology. The most substantiated evidence pertains to irritable bowel syndrome (IBS). The pathogeneses of FM and IBS remain unclear, but it is likely related to dysregulation within the brain-gut axis, resulting in a hyperalgesic state. IBS and FM share other similarities, including a female predominance, fatigue, insomnia, and susceptibility to psychiatric state. These common manifestations and pathogeneses serve as a foundation for overlapping, multidisciplinary treatment modalities.

Original languageEnglish (US)
Pages (from-to)131-142
Number of pages12
JournalRheumatic Disease Clinics of North America
Volume44
Issue number1
DOIs
StatePublished - Feb 1 2018
Externally publishedYes

Keywords

  • Abdominal pain
  • Central sensitization
  • Fibromyalgia
  • Hyperalgesia
  • Irritable bowel syndrome

ASJC Scopus subject areas

  • Rheumatology

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