Ganglion Cell Complex Analysis as a Potential Indicator of Early Neuronal Loss in Idiopathic Intracranial Hypertension

Geetha Athappilly, Ignacio García-Basterra, Flavia Machado-Miller, Thomas R. Hedges, Carlos Mendoza-Santiesteban, Laurel Vuong

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Reliable visual field testing is the gold standard in identifying future vision loss in patients with Idiopathic Intracranial hypertension (IIH). However, when field performance is unreliable, GCC analysis may be useful. We evaluated IIH patients over three visits: initial visit, follow-up visit and a third visit, almost 1 year later. We evaluated mean deviation (MD), GCC and RNFL at presentation and the second visit and compared it to the mean deviation (MD) on fields at the third visit. As early as the second visit, GCC loss correlated with visual field results seen at the third visit.

Original languageEnglish (US)
Pages (from-to)10-17
Number of pages8
JournalNeuro-Ophthalmology
Volume43
Issue number1
DOIs
StatePublished - Jan 2 2019

Keywords

  • ganglion cell analysis
  • Idiopathic Intracranial Hypertension (IIH)
  • Optical Coherence Tomography (OCT)
  • Papilledema
  • pseudotumor cerebri

ASJC Scopus subject areas

  • Ophthalmology
  • Clinical Neurology

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