Abstract
Natamycin (pimaricin) as a 5% suspension, was used sucessfully in 16 of 18 consecutive Fusarium solani corneal ulcers between February 1969 and January 1971. Thirteen of these patients obtained a visual result of 20/40 or better. These results compare favorably with a series of 20 Fusarium ulcers treated with amphotericin B prior to February 1969. Amphotericin B was effective in eliminating the fungus in only seven patients, five of whom retained a visual acuity of 20/40 or better. These results suggest that a 5% suspension of natamycin should be the initial therapy in F solani keratitis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 147-154 |
| Number of pages | 8 |
| Journal | Archives of ophthalmology |
| Volume | 88 |
| Issue number | 2 |
| DOIs | |
| State | Published - Aug 1972 |
Keywords
- Fusarium solani keratitis
- amphotericin B
- antifungal therapy
- corneal ulcer
- mycotic keratitis
- natamycin
- ocular mycoses
ASJC Scopus subject areas
- Ophthalmology
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Jones, D. B., Forster, R. K., & Rebell, G. (1972). Fusarium solani Keratitis Treated With Natamycin (Pimaricin): Eighteen Consecutive Cases. Archives of ophthalmology, 88(2), 147-154. https://doi.org/10.1001/archopht.1972.01000030149004