Fusarium solani Keratitis Treated With Natamycin (Pimaricin): Eighteen Consecutive Cases

Dan B. Jones, Richard K. Forster, Gerbert Rebell

Research output: Contribution to journalArticle

57 Scopus citations

Abstract

Natamycin (pimaricin) as a 5% suspension, was used sucessfully in 16 of 18 consecutive Fusarium solani corneal ulcers between February 1969 and January 1971. Thirteen of these patients obtained a visual result of 20/40 or better. These results compare favorably with a series of 20 Fusarium ulcers treated with amphotericin B prior to February 1969. Amphotericin B was effective in eliminating the fungus in only seven patients, five of whom retained a visual acuity of 20/40 or better. These results suggest that a 5% suspension of natamycin should be the initial therapy in F solani keratitis.

Original languageEnglish (US)
Pages (from-to)147-154
Number of pages8
JournalArchives of ophthalmology
Volume88
Issue number2
DOIs
StatePublished - Aug 1972

Keywords

  • Fusarium solani keratitis
  • amphotericin B
  • antifungal therapy
  • corneal ulcer
  • mycotic keratitis
  • natamycin
  • ocular mycoses

ASJC Scopus subject areas

  • Ophthalmology

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