Fusarium solani Keratitis Treated With Natamycin (Pimaricin): Eighteen Consecutive Cases

Dan B. Jones; Richard K. Forster; Gerbert Rebell

doi:10.1001/archopht.1972.01000030149004

Fusarium solani Keratitis Treated With Natamycin (Pimaricin): Eighteen Consecutive Cases

Dan B. Jones, Richard K. Forster, Gerbert Rebell

Ophthalmology

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

Abstract

Natamycin (pimaricin) as a 5% suspension, was used sucessfully in 16 of 18 consecutive Fusarium solani corneal ulcers between February 1969 and January 1971. Thirteen of these patients obtained a visual result of 20/40 or better. These results compare favorably with a series of 20 Fusarium ulcers treated with amphotericin B prior to February 1969. Amphotericin B was effective in eliminating the fungus in only seven patients, five of whom retained a visual acuity of 20/40 or better. These results suggest that a 5% suspension of natamycin should be the initial therapy in F solani keratitis.

Original language	English (US)
Pages (from-to)	147-154
Number of pages	8
Journal	Archives of ophthalmology
Volume	88
Issue number	2
DOIs	https://doi.org/10.1001/archopht.1972.01000030149004
State	Published - Aug 1972

Keywords

Fusarium solani keratitis
amphotericin B
antifungal therapy
corneal ulcer
mycotic keratitis
natamycin
ocular mycoses

ASJC Scopus subject areas

Ophthalmology

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title = "Fusarium solani Keratitis Treated With Natamycin (Pimaricin): Eighteen Consecutive Cases",

abstract = "Natamycin (pimaricin) as a 5% suspension, was used sucessfully in 16 of 18 consecutive Fusarium solani corneal ulcers between February 1969 and January 1971. Thirteen of these patients obtained a visual result of 20/40 or better. These results compare favorably with a series of 20 Fusarium ulcers treated with amphotericin B prior to February 1969. Amphotericin B was effective in eliminating the fungus in only seven patients, five of whom retained a visual acuity of 20/40 or better. These results suggest that a 5% suspension of natamycin should be the initial therapy in F solani keratitis.",

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KW - ocular mycoses

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Fusarium solani Keratitis Treated With Natamycin (Pimaricin): Eighteen Consecutive Cases

Abstract

Keywords

ASJC Scopus subject areas

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