Fungal keratitis: Risk factors, diagnosis and effective treatment

Jorge Cantu-Dibildox, Eduardo C Alfonso

Research output: Contribution to journalArticlepeer-review


The effective diagnosis and treatment of fungal keratitis remains a challenging area in ocular microbiology. Most of the time the diagnosis is delayed and correct treatment is not instituted, leading to a poor prognosis for visual function. Risk factors, such as trauma, corticosteroid use and underlying eye or systemic disease, are well-known culprits. A recent increase in the number of cases of fungal keratitis, particularly those associated with contact lens use, has caused alarm among both the public and medical communities. The awareness of the clinician, as well as the use of appropriate diagnostic tools, can prevent catastrophic delays in diagnosis. Current treatment advocates the use of powerful antifungal agents, with eye-preserving surgery for nonresponding cases.

Original languageEnglish (US)
Pages (from-to)597-602
Number of pages6
JournalExpert Review of Ophthalmology
Issue number4
StatePublished - Aug 1 2007


  • amphotericin B
  • antifungal agents
  • contact lens
  • fungal
  • Fusarium
  • keratitis
  • ketoconazole
  • nathamycin
  • penetrating keratoplasty

ASJC Scopus subject areas

  • Biomedical Engineering
  • Ophthalmology
  • Optometry


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