TY - JOUR
T1 - Functional biomaterials
T2 - Design of novel biomaterials
AU - Sakiyama-Elbert, S. E.
AU - Hubbell, J. A.
PY - 2001
Y1 - 2001
N2 - The field of biomaterials has recently been focused on the design of intelligent materials. Toward this goal, materials have been developed that can provide specific bioactive signals to control the biological environment around them during the process of materials integration and wound healing. In addition, materials have been developed that can respond to changes in their environment, such as a change in pH or cell-associated enzymatic activity. In designing such novel biomaterials, researchers have sought not merely to create bio-inert materials, but rather materials that can respond to the cellular environment around them to improve device integration and tissue regeneration.
AB - The field of biomaterials has recently been focused on the design of intelligent materials. Toward this goal, materials have been developed that can provide specific bioactive signals to control the biological environment around them during the process of materials integration and wound healing. In addition, materials have been developed that can respond to changes in their environment, such as a change in pH or cell-associated enzymatic activity. In designing such novel biomaterials, researchers have sought not merely to create bio-inert materials, but rather materials that can respond to the cellular environment around them to improve device integration and tissue regeneration.
KW - Cell adhesion
KW - Drug delivery
KW - Gene delivery
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U2 - 10.1146/annurev.matsci.31.1.183
DO - 10.1146/annurev.matsci.31.1.183
M3 - Article
AN - SCOPUS:0035165535
VL - 31
SP - 183
EP - 201
JO - Annual Review of Materials Research
JF - Annual Review of Materials Research
SN - 1531-7331
ER -