Functional biomaterials: Design of novel biomaterials

S. E. Sakiyama-Elbert, J. A. Hubbell

Research output: Contribution to journalArticle

188 Scopus citations

Abstract

The field of biomaterials has recently been focused on the design of intelligent materials. Toward this goal, materials have been developed that can provide specific bioactive signals to control the biological environment around them during the process of materials integration and wound healing. In addition, materials have been developed that can respond to changes in their environment, such as a change in pH or cell-associated enzymatic activity. In designing such novel biomaterials, researchers have sought not merely to create bio-inert materials, but rather materials that can respond to the cellular environment around them to improve device integration and tissue regeneration.

Original languageEnglish (US)
Pages (from-to)183-201
Number of pages19
JournalAnnual Review of Materials Science
Volume31
DOIs
StatePublished - Jan 1 2001

Keywords

  • Cell adhesion
  • Drug delivery
  • Gene delivery

ASJC Scopus subject areas

  • Materials Science(all)

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