Frontal fibrosing alopecia treatment options

Raymond Fertig, Antonella Tosti

Research output: Contribution to journalLetterpeer-review

15 Scopus citations


Frontal fibrosing alopecia (FFA) is a rare dermatologic disease that causes scarring and hair loss and is increasing in prevalence worldwide. FFA patients typically present with hair loss in the frontal scalp region and eyebrows which may be associated with sensations of itching or burning. FFA is a clinically distinct variant of lichen planopilaris (LPP) that affects predominantly postmenopausal women, although men and premenopausal women may also be affected. Early diagnosis and prompt treatment are necessary to prevent definitive scarring and permanent hair loss. Data from retrospective studies indicate that 5-alpha-reductase inhibitors (5aRIs) are effective in stabilizing the disease. In our clinical experience, we have seen optimal results treating FFA patients with oral finasteride in conjunction with hydroxychloroquine, topical calcineurin inhibitors (tacrolimus) and excimer laser in patients with signs of active inflammation.

Original languageEnglish (US)
Pages (from-to)314-315
Number of pages2
JournalIntractable and Rare Diseases Research
Issue number4
StatePublished - 2016


  • Frontal fibrosing alopecia (FFA)
  • finasteride
  • treatment

ASJC Scopus subject areas

  • Medicine(all)


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