From the Archives of the AFIP: Primary Tumors of the Spine: Radiologic-Pathologic Correlation

Mark D. Murpbey, Carol L. Andrews, Donald J. Flemming, H. Thomas Temple, W. Sean Smith, James G. Smirniotopoulos

Research output: Contribution to journalArticle

181 Citations (Scopus)

Abstract

Primary tumors of the spine are relatively infrequent lesions compared with metastatic disease, multiple myeloma, and lymphoma. However, when a solitary lesion of the spine occurs, these neoplasms represent an important group of entities for diagnostic consideration. A wide variety of benign neoplasms can involve the spine, including osteoid osteoma, osteoblastoma, aneurysmal bone cyst, giant cell tumor, enostosis, and osteochondroma. Common primary nonlymphoproliferative malignant neoplasms of the spine include chordoma, chondrosarcoma, Ewing sarcoma or primitive neuroectodermal tumor, and osteosarcoma. The imaging features of these lesions of the spine are often characteristic. These changes include a small sclerotic focus with irregular thorny margins in the vertebral body (enostosis), a small radiolucent nidus with central calcification in the posterior elements of the vertebral body (osteoid osteoma), a large expansile lesion with multiple fluid-fluid levels (aneurysmal bone cyst), and an aggressive mineralized mass (chondroid or osteoid) with osseous and soft-tissue involvement (chondrosarcoma or osteosarcoma). Radiologists should be aware of the appearance of these unusual neoplasms in order to provide a complete differential diagnosis and to guide clinical colleagues in patient treatment.

Original languageEnglish
Pages (from-to)1131-1158
Number of pages28
JournalRadiographics
Volume16
Issue number5
StatePublished - Dec 1 1996
Externally publishedYes

Fingerprint

Spine
Aneurysmal Bone Cysts
Osteoid Osteoma
Chondrosarcoma
Osteosarcoma
Neoplasms
Osteoblastoma
Osteochondroma
Chordoma
Primitive Neuroectodermal Tumors
Giant Cell Tumors
Ewing's Sarcoma
Multiple Myeloma
Lymphoma
Differential Diagnosis
Therapeutics

Keywords

  • Bones, cysts, 30.3183
  • Bones, growth and development, 30.1334
  • Chordoma, 30.327
  • Ewing sarcoma, 30.3281
  • Osteoblastoma, 30.3123
  • Osteochondroma, 30.3113
  • Osteoma, 30.3122
  • Osteosarcoma, 30.322 sarcoma, 30.321

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Murpbey, M. D., Andrews, C. L., Flemming, D. J., Thomas Temple, H., Smith, W. S., & Smirniotopoulos, J. G. (1996). From the Archives of the AFIP: Primary Tumors of the Spine: Radiologic-Pathologic Correlation. Radiographics, 16(5), 1131-1158.

From the Archives of the AFIP : Primary Tumors of the Spine: Radiologic-Pathologic Correlation. / Murpbey, Mark D.; Andrews, Carol L.; Flemming, Donald J.; Thomas Temple, H.; Smith, W. Sean; Smirniotopoulos, James G.

In: Radiographics, Vol. 16, No. 5, 01.12.1996, p. 1131-1158.

Research output: Contribution to journalArticle

Murpbey, MD, Andrews, CL, Flemming, DJ, Thomas Temple, H, Smith, WS & Smirniotopoulos, JG 1996, 'From the Archives of the AFIP: Primary Tumors of the Spine: Radiologic-Pathologic Correlation', Radiographics, vol. 16, no. 5, pp. 1131-1158.
Murpbey MD, Andrews CL, Flemming DJ, Thomas Temple H, Smith WS, Smirniotopoulos JG. From the Archives of the AFIP: Primary Tumors of the Spine: Radiologic-Pathologic Correlation. Radiographics. 1996 Dec 1;16(5):1131-1158.
Murpbey, Mark D. ; Andrews, Carol L. ; Flemming, Donald J. ; Thomas Temple, H. ; Smith, W. Sean ; Smirniotopoulos, James G. / From the Archives of the AFIP : Primary Tumors of the Spine: Radiologic-Pathologic Correlation. In: Radiographics. 1996 ; Vol. 16, No. 5. pp. 1131-1158.
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