Friction coefficient measurement of an in vivo murine cornea

Alison C. Dunn, Juan Manuel Urueña, Enrique Puig, Victor L Perez Quinones, W. Gregory Sawyer

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Ocular tear film mucins and lipids promote lubricity of the corneal surface during ocular movements. The mechanisms of this lubricity are difficult to model and to measure due to the delicate nature of the film itself and the conditions under which it exists. This study describes a kinetic friction coefficient measured between a glass probe and a living mouse eye. A portable custom micro-tribometer was used to prescribe sliding motions and record normal and frictional forces. Friction coefficient measured over both sliding directions resulted in μ = 0.068 under a pressure of approximately 12 kPa. In vivo measurements may enhance the understanding of corneal friction response, as well as provide an empirical friction coefficient for more complex mechanical models.

Original languageEnglish
Pages (from-to)145-149
Number of pages5
JournalTribology Letters
Volume49
Issue number1
DOIs
StatePublished - Jan 1 2013

Fingerprint

cornea
coefficient of friction
Friction
sliding
kinetic friction
tribometers
mice
lipids
Mucins
friction
Lipids
probes
glass
Glass
Kinetics

Keywords

  • Biotribology
  • In vivo friction
  • Mucin lubrication

ASJC Scopus subject areas

  • Mechanical Engineering
  • Mechanics of Materials
  • Surfaces, Coatings and Films
  • Surfaces and Interfaces

Cite this

Dunn, A. C., Urueña, J. M., Puig, E., Perez Quinones, V. L., & Sawyer, W. G. (2013). Friction coefficient measurement of an in vivo murine cornea. Tribology Letters, 49(1), 145-149. https://doi.org/10.1007/s11249-012-0033-6

Friction coefficient measurement of an in vivo murine cornea. / Dunn, Alison C.; Urueña, Juan Manuel; Puig, Enrique; Perez Quinones, Victor L; Sawyer, W. Gregory.

In: Tribology Letters, Vol. 49, No. 1, 01.01.2013, p. 145-149.

Research output: Contribution to journalArticle

Dunn, AC, Urueña, JM, Puig, E, Perez Quinones, VL & Sawyer, WG 2013, 'Friction coefficient measurement of an in vivo murine cornea', Tribology Letters, vol. 49, no. 1, pp. 145-149. https://doi.org/10.1007/s11249-012-0033-6
Dunn AC, Urueña JM, Puig E, Perez Quinones VL, Sawyer WG. Friction coefficient measurement of an in vivo murine cornea. Tribology Letters. 2013 Jan 1;49(1):145-149. https://doi.org/10.1007/s11249-012-0033-6
Dunn, Alison C. ; Urueña, Juan Manuel ; Puig, Enrique ; Perez Quinones, Victor L ; Sawyer, W. Gregory. / Friction coefficient measurement of an in vivo murine cornea. In: Tribology Letters. 2013 ; Vol. 49, No. 1. pp. 145-149.
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