Frequent handling in the neonatal intensive care unit and intraventricular hemorrhage

H. S. Bada, S. B. Korones, E. H. Perry, Kristopher Arheart, M. Pourcyrous, J. W. Runyan, G. D. Anderson, H. L. Magill, C. W. Fitch, G. W. Somes

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

The association between periventricular-intraventricular hemorrhage (PV-IVH) and frequent handling resulting from various neonatal intensive care procedures and routine interventions was evaluated in a prospective clinical study. Inborn premature babies with birth weight ≤1500 gm (n = 156) who did not have PV-IVH or who had grade 1 PV-IVH at ≤1 hour were randomly assigned to the reduced manipulation protocol (n = 62) or to standard care (n = 94). A bedside microcomputer-based data acquisition system was used to monitor the duration of rest or the number of interventions per day. Infants assigned to receive reduced manipulation spent a significantly higher percentage of time each day at rest than did those who received standard manipulation (p < 0.006). However, the incidence of grades 2 to 4 PV-IVH did not differ significantly (30% in the study vs 37% in the standard manipulation group). When we analyzed the effect of manipulation in relation to risk of PV-IVH, while taking into account other perinatal variables, standard manipulation was not associated with increased risk of grades 2 to 4 PV-IVH. However, low birth weight, maternal smoking, general anesthesia, early grade 1 PV-IVH, low hematocrit, lowest arterial oxygen pressure within the first 6 hours of life, and large base deficit at 6 hours of age all increased the relative risk of grades 2 to 4 PV-IVH.

Original languageEnglish
Pages (from-to)126-131
Number of pages6
JournalJournal of Pediatrics
Volume117
Issue number1 I
StatePublished - Jan 1 1990
Externally publishedYes

Fingerprint

Neonatal Intensive Care Units
Hemorrhage
Neonatal Intensive Care
Handling (Psychology)
Microcomputers
Low Birth Weight Infant
Hematocrit
Information Systems
Birth Weight
General Anesthesia
Arterial Pressure
Smoking
Mothers
Prospective Studies
Oxygen
Incidence

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Bada, H. S., Korones, S. B., Perry, E. H., Arheart, K., Pourcyrous, M., Runyan, J. W., ... Somes, G. W. (1990). Frequent handling in the neonatal intensive care unit and intraventricular hemorrhage. Journal of Pediatrics, 117(1 I), 126-131.

Frequent handling in the neonatal intensive care unit and intraventricular hemorrhage. / Bada, H. S.; Korones, S. B.; Perry, E. H.; Arheart, Kristopher; Pourcyrous, M.; Runyan, J. W.; Anderson, G. D.; Magill, H. L.; Fitch, C. W.; Somes, G. W.

In: Journal of Pediatrics, Vol. 117, No. 1 I, 01.01.1990, p. 126-131.

Research output: Contribution to journalArticle

Bada, HS, Korones, SB, Perry, EH, Arheart, K, Pourcyrous, M, Runyan, JW, Anderson, GD, Magill, HL, Fitch, CW & Somes, GW 1990, 'Frequent handling in the neonatal intensive care unit and intraventricular hemorrhage', Journal of Pediatrics, vol. 117, no. 1 I, pp. 126-131.
Bada HS, Korones SB, Perry EH, Arheart K, Pourcyrous M, Runyan JW et al. Frequent handling in the neonatal intensive care unit and intraventricular hemorrhage. Journal of Pediatrics. 1990 Jan 1;117(1 I):126-131.
Bada, H. S. ; Korones, S. B. ; Perry, E. H. ; Arheart, Kristopher ; Pourcyrous, M. ; Runyan, J. W. ; Anderson, G. D. ; Magill, H. L. ; Fitch, C. W. ; Somes, G. W. / Frequent handling in the neonatal intensive care unit and intraventricular hemorrhage. In: Journal of Pediatrics. 1990 ; Vol. 117, No. 1 I. pp. 126-131.
@article{76e9994977104725ad1c16670c18ac52,
title = "Frequent handling in the neonatal intensive care unit and intraventricular hemorrhage",
abstract = "The association between periventricular-intraventricular hemorrhage (PV-IVH) and frequent handling resulting from various neonatal intensive care procedures and routine interventions was evaluated in a prospective clinical study. Inborn premature babies with birth weight ≤1500 gm (n = 156) who did not have PV-IVH or who had grade 1 PV-IVH at ≤1 hour were randomly assigned to the reduced manipulation protocol (n = 62) or to standard care (n = 94). A bedside microcomputer-based data acquisition system was used to monitor the duration of rest or the number of interventions per day. Infants assigned to receive reduced manipulation spent a significantly higher percentage of time each day at rest than did those who received standard manipulation (p < 0.006). However, the incidence of grades 2 to 4 PV-IVH did not differ significantly (30{\%} in the study vs 37{\%} in the standard manipulation group). When we analyzed the effect of manipulation in relation to risk of PV-IVH, while taking into account other perinatal variables, standard manipulation was not associated with increased risk of grades 2 to 4 PV-IVH. However, low birth weight, maternal smoking, general anesthesia, early grade 1 PV-IVH, low hematocrit, lowest arterial oxygen pressure within the first 6 hours of life, and large base deficit at 6 hours of age all increased the relative risk of grades 2 to 4 PV-IVH.",
author = "Bada, {H. S.} and Korones, {S. B.} and Perry, {E. H.} and Kristopher Arheart and M. Pourcyrous and Runyan, {J. W.} and Anderson, {G. D.} and Magill, {H. L.} and Fitch, {C. W.} and Somes, {G. W.}",
year = "1990",
month = "1",
day = "1",
language = "English",
volume = "117",
pages = "126--131",
journal = "Journal of Pediatrics",
issn = "0022-3476",
publisher = "Mosby Inc.",
number = "1 I",

}

TY - JOUR

T1 - Frequent handling in the neonatal intensive care unit and intraventricular hemorrhage

AU - Bada, H. S.

AU - Korones, S. B.

AU - Perry, E. H.

AU - Arheart, Kristopher

AU - Pourcyrous, M.

AU - Runyan, J. W.

AU - Anderson, G. D.

AU - Magill, H. L.

AU - Fitch, C. W.

AU - Somes, G. W.

PY - 1990/1/1

Y1 - 1990/1/1

N2 - The association between periventricular-intraventricular hemorrhage (PV-IVH) and frequent handling resulting from various neonatal intensive care procedures and routine interventions was evaluated in a prospective clinical study. Inborn premature babies with birth weight ≤1500 gm (n = 156) who did not have PV-IVH or who had grade 1 PV-IVH at ≤1 hour were randomly assigned to the reduced manipulation protocol (n = 62) or to standard care (n = 94). A bedside microcomputer-based data acquisition system was used to monitor the duration of rest or the number of interventions per day. Infants assigned to receive reduced manipulation spent a significantly higher percentage of time each day at rest than did those who received standard manipulation (p < 0.006). However, the incidence of grades 2 to 4 PV-IVH did not differ significantly (30% in the study vs 37% in the standard manipulation group). When we analyzed the effect of manipulation in relation to risk of PV-IVH, while taking into account other perinatal variables, standard manipulation was not associated with increased risk of grades 2 to 4 PV-IVH. However, low birth weight, maternal smoking, general anesthesia, early grade 1 PV-IVH, low hematocrit, lowest arterial oxygen pressure within the first 6 hours of life, and large base deficit at 6 hours of age all increased the relative risk of grades 2 to 4 PV-IVH.

AB - The association between periventricular-intraventricular hemorrhage (PV-IVH) and frequent handling resulting from various neonatal intensive care procedures and routine interventions was evaluated in a prospective clinical study. Inborn premature babies with birth weight ≤1500 gm (n = 156) who did not have PV-IVH or who had grade 1 PV-IVH at ≤1 hour were randomly assigned to the reduced manipulation protocol (n = 62) or to standard care (n = 94). A bedside microcomputer-based data acquisition system was used to monitor the duration of rest or the number of interventions per day. Infants assigned to receive reduced manipulation spent a significantly higher percentage of time each day at rest than did those who received standard manipulation (p < 0.006). However, the incidence of grades 2 to 4 PV-IVH did not differ significantly (30% in the study vs 37% in the standard manipulation group). When we analyzed the effect of manipulation in relation to risk of PV-IVH, while taking into account other perinatal variables, standard manipulation was not associated with increased risk of grades 2 to 4 PV-IVH. However, low birth weight, maternal smoking, general anesthesia, early grade 1 PV-IVH, low hematocrit, lowest arterial oxygen pressure within the first 6 hours of life, and large base deficit at 6 hours of age all increased the relative risk of grades 2 to 4 PV-IVH.

UR - http://www.scopus.com/inward/record.url?scp=0025338789&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025338789&partnerID=8YFLogxK

M3 - Article

C2 - 2196354

AN - SCOPUS:0025338789

VL - 117

SP - 126

EP - 131

JO - Journal of Pediatrics

JF - Journal of Pediatrics

SN - 0022-3476

IS - 1 I

ER -