Abstract
In six normal subjects we investigated the effects of oral phosphatidylcholine (lecithin) on the concentrations of plasma choline, erythrocyte choline, and choline-containing lipids. Plasma choline levels rose 1 hr after treatment and remained elevated for 8 hr, with peaks at 3 and 4 hr after phosphatidylcholine. Erythrocyte choline levels also rose, although the rise was slightly delayed relative to plasma choline. There was no change in the plasma choline-containing lipid concentration. These results demonstrate that, in normal subjects, oral phosphatidylcholine induces prolonged rises in plasma and erythrocyte choline concentrations and is therefore useful when such effects are desired.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 483-487 |
| Number of pages | 5 |
| Journal | Clinical Pharmacology and Therapeutics |
| Volume | 31 |
| Issue number | 4 |
| DOIs | |
| State | Published - Apr 1982 |
ASJC Scopus subject areas
- Pharmacology
- Pharmacology (medical)
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Cite this
Jope, R. S., Domino, E. F., Mathews, B. N., Sitaram, N., Jenden, D. J., & Ortez, A. (1982). Free and bound choline blood levels after phosphatidylcholine. Clinical Pharmacology and Therapeutics, 31(4), 483-487. https://doi.org/10.1038/clpt.1982.64