The novel concept of 'fractional photothermolysis' was introduced to the market in 2003, and has since gained tremendous popularity and importance for numerous clinical indications. Its development and introduction were driven by the need for an effective yet safe and low-risk resurfacing technique, in contrast to the ablative and non-ablative lasers available at the time. The first device that was introduced to the market used non-ablative wavelengths. In 2007, the technology was further developed with ablative wavelengths leading to vaporization of tissue. This new technology has revolutionized the field of laser skin resurfacing and resulted in the development of numerous non-ablative and ablative fractional devices. There is little doubt that fractional technology is here to stay, as (when used properly) it allows the operator to obtain significant clinical results with minimal post-treatment recovery and hence fewer complications.