Abstract
Purpose To correlate visual acuity to macular spectral-domain optical coherence tomography (SD OCT) anomalies detected in children with a history of retinopathy of prematurity (ROP). Design Retrospective cohort study. Methods All charts of children with a history of ROP between 2 and 18 years of age and with SD OCT performed between 2010 and 2012 were reviewed. Central foveal thickness was measured and correlated with visual acuity. Secondary outcome measures included temporal parafoveal thickness, presence of the inner nuclear layer and outer segment, gestational age at birth, sex, spherical equivalent, history of laser treatment, and developmental delay. Results The study included 44 better-seeing eyes of 44 patients. Sixty-four percent (28/44) of patients in our study had 20/40 or better visual acuity despite an abnormal foveal morphology in 91% of total eyes. Conclusion Patients with a history of ROP demonstrate a high frequency of macular morphologic abnormalities, including retention of inner retinal layers and absent foveal depression, on SD OCT. These structural changes do not always correlate to visual acuity. Instead it appears that cone maturation may be a better indicator of visual acuity. In addition, there is a significant correlation between best-corrected visual acuity and myopia.
| Original language | English |
|---|---|
| Journal | American Journal of Ophthalmology |
| Volume | 158 |
| Issue number | 3 |
| DOIs | |
| State | Published - Jan 1 2014 |
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ASJC Scopus subject areas
- Ophthalmology
Cite this
Foveal structure-function correlation in children with history of retinopathy of prematurity. / Villegas, Victor M.; Capo, Hilda; Cavuoto, Kara M; McKeown, Craig; Berrocal, Audina.
In: American Journal of Ophthalmology, Vol. 158, No. 3, 01.01.2014.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Foveal structure-function correlation in children with history of retinopathy of prematurity
AU - Villegas, Victor M.
AU - Capo, Hilda
AU - Cavuoto, Kara M
AU - McKeown, Craig
AU - Berrocal, Audina
PY - 2014/1/1
Y1 - 2014/1/1
N2 - Purpose To correlate visual acuity to macular spectral-domain optical coherence tomography (SD OCT) anomalies detected in children with a history of retinopathy of prematurity (ROP). Design Retrospective cohort study. Methods All charts of children with a history of ROP between 2 and 18 years of age and with SD OCT performed between 2010 and 2012 were reviewed. Central foveal thickness was measured and correlated with visual acuity. Secondary outcome measures included temporal parafoveal thickness, presence of the inner nuclear layer and outer segment, gestational age at birth, sex, spherical equivalent, history of laser treatment, and developmental delay. Results The study included 44 better-seeing eyes of 44 patients. Sixty-four percent (28/44) of patients in our study had 20/40 or better visual acuity despite an abnormal foveal morphology in 91% of total eyes. Conclusion Patients with a history of ROP demonstrate a high frequency of macular morphologic abnormalities, including retention of inner retinal layers and absent foveal depression, on SD OCT. These structural changes do not always correlate to visual acuity. Instead it appears that cone maturation may be a better indicator of visual acuity. In addition, there is a significant correlation between best-corrected visual acuity and myopia.
AB - Purpose To correlate visual acuity to macular spectral-domain optical coherence tomography (SD OCT) anomalies detected in children with a history of retinopathy of prematurity (ROP). Design Retrospective cohort study. Methods All charts of children with a history of ROP between 2 and 18 years of age and with SD OCT performed between 2010 and 2012 were reviewed. Central foveal thickness was measured and correlated with visual acuity. Secondary outcome measures included temporal parafoveal thickness, presence of the inner nuclear layer and outer segment, gestational age at birth, sex, spherical equivalent, history of laser treatment, and developmental delay. Results The study included 44 better-seeing eyes of 44 patients. Sixty-four percent (28/44) of patients in our study had 20/40 or better visual acuity despite an abnormal foveal morphology in 91% of total eyes. Conclusion Patients with a history of ROP demonstrate a high frequency of macular morphologic abnormalities, including retention of inner retinal layers and absent foveal depression, on SD OCT. These structural changes do not always correlate to visual acuity. Instead it appears that cone maturation may be a better indicator of visual acuity. In addition, there is a significant correlation between best-corrected visual acuity and myopia.
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UR - http://www.scopus.com/inward/citedby.url?scp=84908374627&partnerID=8YFLogxK
U2 - 10.1016/j.ajo.2014.05.017
DO - 10.1016/j.ajo.2014.05.017
M3 - Article
C2 - 24874998
AN - SCOPUS:84908374627
VL - 158
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
SN - 0002-9394
IS - 3
ER -