Formulary considerations for treating psychiatric disorders: Schizophrenia

E. Risby, D. Donnigan, C. B. Nemeroff

Research output: Contribution to journalReview articlepeer-review

Abstract

Schizophrenia is a severe psychiatric disorder that causes major public health problems. Pharmacotherapy for the condition is divided into two groups: conventional (neuroleptic) and atypical antipsychotics. Conventional agents are effective against positive symptoms of schizophrenia and have a low acquisition cost; however, the risk of significant adverse effects-extrapyramidal symptoms, tardive dyskinesia, and neuroleptic malignant syndrome-limit their use. Atypical antipsychotics, however, appear to provide greater efficacy, including effectiveness against both positive and negative symptoms, than the neuroleptics and, in general, have a more favorable side effect profile. This article reviews both the conventional and atypical treatments available for the treatment of schizophrenia.

Original languageEnglish (US)
Pages (from-to)142-155
Number of pages14
JournalFormulary
Volume32
Issue number2
StatePublished - Jan 1 1997
Externally publishedYes

ASJC Scopus subject areas

  • Pharmacology (medical)

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