Focal neuropathy preceding chronic inflammatory demyelinating polyradiculoneuropathy by several years

A. Verma, R. Tandan, A. M. Adesina, W. W. Pendlebury, T. J. Fries, W. G. Bradley

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

We report three patients who exhibited an unusual clinical course of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) in which mononeuropathic limb weakness developed 2, 11 and 23 years, respectively, before the development of generalized polyradiculoneuropathy. The eventual diagnosis remained uncertain until other causes of neuropathy were excluded, and the clinical disorder progressed to involve the other limbs. Focal or regional variants of CIDP suggest that the pathologic, and perhaps the immunologic, abnormalities can be localized and selective for prolonged periods of time. Although this clinical variant seems to account for a small number of CIDP cases, its recognition may aid in making an early diagnosis.

Original languageEnglish (US)
Pages (from-to)516-521
Number of pages6
JournalActa Neurologica Scandinavica
Volume81
Issue number6
DOIs
StatePublished - Jun 1990
Externally publishedYes

Keywords

  • AIDP
  • CIDP
  • conduction block
  • demyelination
  • mononeuropathy

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Fingerprint Dive into the research topics of 'Focal neuropathy preceding chronic inflammatory demyelinating polyradiculoneuropathy by several years'. Together they form a unique fingerprint.

  • Cite this