Focal liver lesions: MR imaging-pathologic correlation

C. Bartolozzi, D. Cioni, F. Donati, R. Lencioni

Research output: Contribution to journalArticle

98 Scopus citations

Abstract

Magnetic resonance signal intensity of focal liver lesions is affected by numerous pathologic factors. Lesion histologic features, such as cellularity, vascularity, stromal component, and intratumoral necrosis or hemorrhage, strongly affect T1 and T2 relaxation times. Additionally, intracellular content of certain substances, such as glycogen, fat, melanin, iron, and copper, may also have a substantial role in determining MR signal behavior. In this review we discuss the correlations between MR imaging features and pathologic findings in benign and malignant focal liver lesions. Knowledge of imaging-pathology correlations greatly assist in characterizing focal lesions. Moreover, in certain tumor histotypes, such as hepatocellular carcinoma, careful analysis of lesion signal intensity may help predict the degree of tumor differentiation.

Original languageEnglish (US)
Pages (from-to)1374-1388
Number of pages15
JournalEuropean Radiology
Volume11
Issue number8
DOIs
StatePublished - Aug 29 2001

Keywords

  • Liver
  • Liver neoplasms
  • MR imaging diagnosis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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    Bartolozzi, C., Cioni, D., Donati, F., & Lencioni, R. (2001). Focal liver lesions: MR imaging-pathologic correlation. European Radiology, 11(8), 1374-1388. https://doi.org/10.1007/s003300100845