Fluorescein angiography findings in diffuse retinoblastoma: two case reports with clinicopathologic correlation

Maria P. Fernandez, Shaza N. Al-Holou, Oliver Fischer, Timothy Murray, J. William Harbour, Sander Dubovy, Audina Berrocal

Research output: Contribution to journalArticle

3 Scopus citations


Whereas most retinoblastomas are seen as intraocular tumors, the diffuse infiltrating type is distinguished by a horizontal growth along the retina with minimal vertical growth. These findings can resemble other entities and present as a diagnostic challenge. Fluorescein angiography (FA) features of retinoblastoma have been described in the literature; however, to our knowledge, little information is available on the diffuse type. We present FA findings and the clinicopathlogic correlation of 2 patients with diffuse retinoblastoma. Changes observed on FA correlate with the vascular changes observed on histopathology and can therefore be helpful in the diagnosis of atypical retinoblastomas when the clinical presentation is equivocal. [Figure presented]

Original languageEnglish (US)
Pages (from-to)337-339.e2
JournalJournal of AAPOS
Issue number4
StatePublished - Aug 1 2017


ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Ophthalmology

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