Flow-area relationship in internal carotid and vertebral arteries

J. R. Cebral, M. A. Castro, C. M. Putman, N. Alperin

Research output: Contribution to journalArticlepeer-review

120 Scopus citations


Subject-specific computational and experimental models of hemodynamics in cerebral aneurysms require the specification of physiologic flow conditions. Because patient-specific flow data are not always available, researchers have used 'typical' or population average flow rates and waveforms. However, in order to be able to compare the magnitude of hemodynamic variables between different aneurysms or groups of aneurysms (e.g. ruptured versus unruptured) it is necessary to scale the flow rates to the area of the inflow artery. In this work, a relationship between flow rates and vessel areas is derived from phase-contrast magnetic resonance measurements in the internal carotid arteries and vertebral arteries of normal subjects.

Original languageEnglish (US)
Pages (from-to)585-594
Number of pages10
JournalPhysiological Measurement
Issue number5
StatePublished - May 1 2008
Externally publishedYes


  • Blood flow
  • Carotid artery
  • Cerebral aneurysm
  • Magnetic resonance imaging
  • Vertebral artery
  • Wall shear stress

ASJC Scopus subject areas

  • Biophysics


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