FK506-induced leukoencephalopathy in children with organ transplants

H. V. Torocsik, Richard G. Curless, J. Post, A. G. Tzakis, L. Pearse

Research output: Contribution to journalArticle

46 Scopus citations


FK506-induced leukoencephalopathy is a well-known entity in adult organ transplant patients. The neurotoxicity of FK506 immunosuppression is frequently reversible, with either reduction or cessation of the drug. This neurologic syndrome is not well documented in children. We report the clinical and radiologic features in four pediatric cases of FK506 leukoencephalopathy. In two of the four patients this syndrome was reversible.

Original languageEnglish (US)
Pages (from-to)1497-1500
Number of pages4
Issue number7
StatePublished - Apr 22 1999


ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Torocsik, H. V., Curless, R. G., Post, J., Tzakis, A. G., & Pearse, L. (1999). FK506-induced leukoencephalopathy in children with organ transplants. Neurology, 52(7), 1497-1500.