FK506-induced leukoencephalopathy in children with organ transplants

H. V. Torocsik, Richard G. Curless, M. Judith Post, A. G. Tzakis, L. Pearse

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

FK506-induced leukoencephalopathy is a well-known entity in adult organ transplant patients. The neurotoxicity of FK506 immunosuppression is frequently reversible, with either reduction or cessation of the drug. This neurologic syndrome is not well documented in children. We report the clinical and radiologic features in four pediatric cases of FK506 leukoencephalopathy. In two of the four patients this syndrome was reversible.

Original languageEnglish
Pages (from-to)1497-1500
Number of pages4
JournalNeurology
Volume52
Issue number7
StatePublished - Apr 22 1999
Externally publishedYes

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Leukoencephalopathies
Tacrolimus
Transplants
Immunosuppression
Nervous System
Pediatrics
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Torocsik, H. V., Curless, R. G., Judith Post, M., Tzakis, A. G., & Pearse, L. (1999). FK506-induced leukoencephalopathy in children with organ transplants. Neurology, 52(7), 1497-1500.

FK506-induced leukoencephalopathy in children with organ transplants. / Torocsik, H. V.; Curless, Richard G.; Judith Post, M.; Tzakis, A. G.; Pearse, L.

In: Neurology, Vol. 52, No. 7, 22.04.1999, p. 1497-1500.

Research output: Contribution to journalArticle

Torocsik, HV, Curless, RG, Judith Post, M, Tzakis, AG & Pearse, L 1999, 'FK506-induced leukoencephalopathy in children with organ transplants', Neurology, vol. 52, no. 7, pp. 1497-1500.
Torocsik HV, Curless RG, Judith Post M, Tzakis AG, Pearse L. FK506-induced leukoencephalopathy in children with organ transplants. Neurology. 1999 Apr 22;52(7):1497-1500.
Torocsik, H. V. ; Curless, Richard G. ; Judith Post, M. ; Tzakis, A. G. ; Pearse, L. / FK506-induced leukoencephalopathy in children with organ transplants. In: Neurology. 1999 ; Vol. 52, No. 7. pp. 1497-1500.
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