First locally acquired congenital zika syndrome case in the United States: Neonatal clinical manifestations

Camila V. Ventura, Emmalee S Bandstra, Maria P. Fernandez, Joshua M. Cooper, Gaurav Saigal, Charles R Bauer, Julie A. Hofheimer, Michelle Berkovits, Robert Fifer, Alyssa Pensirikul, Ivan Gonzalez, Christine Curry, Samita Andreansky, Ramzi T Younis, Xue Z Liu, Tanuj Banker, Sander Dubovy, Samantha M. Langer, Audina Berrocal

Research output: Contribution to journalArticle

3 Scopus citations


In the spring of 2017, a full-term infant with microcephaly was delivered in South Florida. During first trimester, the mother presented with fever, nausea, and vomiting. She reported no foreign travel for herself or her partner. The infant's neurologic, ophthalmologic, neuroradiologic, and audiologic findings were highly suggestive of congenital Zika syndrome (CZS), confirmed by IgM antibodies and plaque reduction neutralization test. New observations, including peripheral temporal retinal avascularity and peripapillary retinal nerve fiber layer thinning, are presented from this first known case of non-travel-associated CZS in the United States.

Original languageEnglish (US)
Pages (from-to)e93-e98
JournalOphthalmic Surgery Lasers and Imaging Retina
Issue number9
StatePublished - Sep 1 2018


ASJC Scopus subject areas

  • Surgery
  • Ophthalmology

Cite this