Abstract
Purpose: To estimate the theoretical corneal refractive error induced by mechanical weakening effects from posterior lamellar keratoplasty (PLKP) in the human cornea. Methods: The refractive effects of PLKP are simulated by finite-element modeling (FEM) as a mathematical function of the thickness of the excised posterior lamellar corneal button, with a nonlinear formulation of stress-strain relation for the corneal material. A theoretical nomogram was developed to correlate the refractive changes to button thickness. Results: The predicted refractive change after PLKP is less than 1 dpt for a 170-μm thickness posterior corneal button over a broad range of Young's modulus. Thicker buttons result in greater surgically induced refractive errors. Conclusions: According to FEM analysis, the excision of a posterior lamellar button of less than 170 μm thickness produces a minimal predicted refractive change (
| Original language | English (US) |
|---|---|
| Pages (from-to) | 329-334 |
| Number of pages | 6 |
| Journal | Ophthalmic Research |
| Volume | 38 |
| Issue number | 6 |
| DOIs | |
| State | Published - Nov 2006 |
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Keywords
- Posterior lamellar keratoplasty, mathematical modeling
- Refractive error
ASJC Scopus subject areas
- Ophthalmology
Cite this
Finite-element modeling of posterior lamellar keratoplasty : Construction of theoretical nomograms for induced refractive errors. / Djotyan, Gagik P.; Soong, H. Kaz; Mian, Shahzad; Cabrera DeBuc, Delia; Kurtz, Ronald M.; Juhasz, Tibor.
In: Ophthalmic Research, Vol. 38, No. 6, 11.2006, p. 329-334.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Finite-element modeling of posterior lamellar keratoplasty
T2 - Construction of theoretical nomograms for induced refractive errors
AU - Djotyan, Gagik P.
AU - Soong, H. Kaz
AU - Mian, Shahzad
AU - Cabrera DeBuc, Delia
AU - Kurtz, Ronald M.
AU - Juhasz, Tibor
PY - 2006/11
Y1 - 2006/11
N2 - Purpose: To estimate the theoretical corneal refractive error induced by mechanical weakening effects from posterior lamellar keratoplasty (PLKP) in the human cornea. Methods: The refractive effects of PLKP are simulated by finite-element modeling (FEM) as a mathematical function of the thickness of the excised posterior lamellar corneal button, with a nonlinear formulation of stress-strain relation for the corneal material. A theoretical nomogram was developed to correlate the refractive changes to button thickness. Results: The predicted refractive change after PLKP is less than 1 dpt for a 170-μm thickness posterior corneal button over a broad range of Young's modulus. Thicker buttons result in greater surgically induced refractive errors. Conclusions: According to FEM analysis, the excision of a posterior lamellar button of less than 170 μm thickness produces a minimal predicted refractive change (
AB - Purpose: To estimate the theoretical corneal refractive error induced by mechanical weakening effects from posterior lamellar keratoplasty (PLKP) in the human cornea. Methods: The refractive effects of PLKP are simulated by finite-element modeling (FEM) as a mathematical function of the thickness of the excised posterior lamellar corneal button, with a nonlinear formulation of stress-strain relation for the corneal material. A theoretical nomogram was developed to correlate the refractive changes to button thickness. Results: The predicted refractive change after PLKP is less than 1 dpt for a 170-μm thickness posterior corneal button over a broad range of Young's modulus. Thicker buttons result in greater surgically induced refractive errors. Conclusions: According to FEM analysis, the excision of a posterior lamellar button of less than 170 μm thickness produces a minimal predicted refractive change (
KW - Posterior lamellar keratoplasty, mathematical modeling
KW - Refractive error
UR - http://www.scopus.com/inward/record.url?scp=33750688893&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33750688893&partnerID=8YFLogxK
U2 - 10.1159/000096227
DO - 10.1159/000096227
M3 - Article
C2 - 17047405
AN - SCOPUS:33750688893
VL - 38
SP - 329
EP - 334
JO - Ophthalmic Research
JF - Ophthalmic Research
SN - 0030-3747
IS - 6
ER -