Finite-element modeling of posterior lamellar keratoplasty: Construction of theoretical nomograms for induced refractive errors

Gagik P. Djotyan, H. Kaz Soong, Shahzad Mian, Delia C. Fernández, Ronald M. Kurtz, Tibor Juhasz

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Purpose: To estimate the theoretical corneal refractive error induced by mechanical weakening effects from posterior lamellar keratoplasty (PLKP) in the human cornea. Methods: The refractive effects of PLKP are simulated by finite-element modeling (FEM) as a mathematical function of the thickness of the excised posterior lamellar corneal button, with a nonlinear formulation of stress-strain relation for the corneal material. A theoretical nomogram was developed to correlate the refractive changes to button thickness. Results: The predicted refractive change after PLKP is less than 1 dpt for a 170-μm thickness posterior corneal button over a broad range of Young's modulus. Thicker buttons result in greater surgically induced refractive errors. Conclusions: According to FEM analysis, the excision of a posterior lamellar button of less than 170 μm thickness produces a minimal predicted refractive change (<1 dpt) in the cornea after PLKP.

Original languageEnglish (US)
Pages (from-to)329-334
Number of pages6
JournalOphthalmic Research
Volume38
Issue number6
DOIs
StatePublished - Nov 1 2006

Keywords

  • Posterior lamellar keratoplasty, mathematical modeling
  • Refractive error

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

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