Finite-element modeling of posterior lamellar keratoplasty: Construction of theoretical nomograms for induced refractive errors

Gagik P. Djotyan, H. Kaz Soong, Shahzad Mian, Delia Cabrera DeBuc, Ronald M. Kurtz, Tibor Juhasz

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Purpose: To estimate the theoretical corneal refractive error induced by mechanical weakening effects from posterior lamellar keratoplasty (PLKP) in the human cornea. Methods: The refractive effects of PLKP are simulated by finite-element modeling (FEM) as a mathematical function of the thickness of the excised posterior lamellar corneal button, with a nonlinear formulation of stress-strain relation for the corneal material. A theoretical nomogram was developed to correlate the refractive changes to button thickness. Results: The predicted refractive change after PLKP is less than 1 dpt for a 170-μm thickness posterior corneal button over a broad range of Young's modulus. Thicker buttons result in greater surgically induced refractive errors. Conclusions: According to FEM analysis, the excision of a posterior lamellar button of less than 170 μm thickness produces a minimal predicted refractive change (

Original languageEnglish (US)
Pages (from-to)329-334
Number of pages6
JournalOphthalmic Research
Volume38
Issue number6
DOIs
StatePublished - Nov 2006

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Nomograms
Corneal Transplantation
Refractive Errors
Finite Element Analysis
Elastic Modulus
Cornea

Keywords

  • Posterior lamellar keratoplasty, mathematical modeling
  • Refractive error

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Finite-element modeling of posterior lamellar keratoplasty : Construction of theoretical nomograms for induced refractive errors. / Djotyan, Gagik P.; Soong, H. Kaz; Mian, Shahzad; Cabrera DeBuc, Delia; Kurtz, Ronald M.; Juhasz, Tibor.

In: Ophthalmic Research, Vol. 38, No. 6, 11.2006, p. 329-334.

Research output: Contribution to journalArticle

Djotyan, Gagik P. ; Soong, H. Kaz ; Mian, Shahzad ; Cabrera DeBuc, Delia ; Kurtz, Ronald M. ; Juhasz, Tibor. / Finite-element modeling of posterior lamellar keratoplasty : Construction of theoretical nomograms for induced refractive errors. In: Ophthalmic Research. 2006 ; Vol. 38, No. 6. pp. 329-334.
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