Finite-element modeling of posterior lamellar keratoplasty

Construction of theoretical nomograms for induced refractive errors

Gagik P. Djotyan, H. Kaz Soong, Shahzad Mian, Delia Cabrera DeBuc, Ronald M. Kurtz, Tibor Juhasz

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Purpose: To estimate the theoretical corneal refractive error induced by mechanical weakening effects from posterior lamellar keratoplasty (PLKP) in the human cornea. Methods: The refractive effects of PLKP are simulated by finite-element modeling (FEM) as a mathematical function of the thickness of the excised posterior lamellar corneal button, with a nonlinear formulation of stress-strain relation for the corneal material. A theoretical nomogram was developed to correlate the refractive changes to button thickness. Results: The predicted refractive change after PLKP is less than 1 dpt for a 170-μm thickness posterior corneal button over a broad range of Young's modulus. Thicker buttons result in greater surgically induced refractive errors. Conclusions: According to FEM analysis, the excision of a posterior lamellar button of less than 170 μm thickness produces a minimal predicted refractive change (

Original languageEnglish (US)
Pages (from-to)329-334
Number of pages6
JournalOphthalmic Research
Volume38
Issue number6
DOIs
StatePublished - Nov 2006

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Nomograms
Corneal Transplantation
Refractive Errors
Finite Element Analysis
Elastic Modulus
Cornea

Keywords

  • Posterior lamellar keratoplasty, mathematical modeling
  • Refractive error

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Finite-element modeling of posterior lamellar keratoplasty : Construction of theoretical nomograms for induced refractive errors. / Djotyan, Gagik P.; Soong, H. Kaz; Mian, Shahzad; Cabrera DeBuc, Delia; Kurtz, Ronald M.; Juhasz, Tibor.

In: Ophthalmic Research, Vol. 38, No. 6, 11.2006, p. 329-334.

Research output: Contribution to journalArticle

Djotyan, Gagik P. ; Soong, H. Kaz ; Mian, Shahzad ; Cabrera DeBuc, Delia ; Kurtz, Ronald M. ; Juhasz, Tibor. / Finite-element modeling of posterior lamellar keratoplasty : Construction of theoretical nomograms for induced refractive errors. In: Ophthalmic Research. 2006 ; Vol. 38, No. 6. pp. 329-334.
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