Fine-tuning the prediction of sequences cleaved by signal peptidase II

A curated set of proven and predicted lipoproteins of Escherichia coli K-12

Pedro Gonnet, Kenneth E. Rudd, Frédérique Lisacek

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

A curated set of 81 proven and 44 predicted lipoproteins of Escherichia coli K-12 was defined with the combined use of a literature survey, a variety of predictive tools and human expertise. The well-documented Gram-negative proteome of E. coli K-12 was chosen to assess how the different approaches complement each other and to ensure a stable definition of a consistent set of lipoproteins. The results of detailed analysis of such proteins at the level of a single proteome are presented, corroborated and rationalized.

Original languageEnglish
Pages (from-to)1597-1613
Number of pages17
JournalProteomics
Volume4
Issue number6
DOIs
StatePublished - Jun 1 2004
Externally publishedYes

Fingerprint

Proteome
Escherichia coli
Lipoproteins
Tuning
Proteins
signal peptidase II
Surveys and Questionnaires

Keywords

  • Bacterial proteome
  • Curated set
  • Lipoprotein
  • Signal prediction

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

Cite this

Fine-tuning the prediction of sequences cleaved by signal peptidase II : A curated set of proven and predicted lipoproteins of Escherichia coli K-12. / Gonnet, Pedro; Rudd, Kenneth E.; Lisacek, Frédérique.

In: Proteomics, Vol. 4, No. 6, 01.06.2004, p. 1597-1613.

Research output: Contribution to journalArticle

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