Abstract
A curated set of 81 proven and 44 predicted lipoproteins of Escherichia coli K-12 was defined with the combined use of a literature survey, a variety of predictive tools and human expertise. The well-documented Gram-negative proteome of E. coli K-12 was chosen to assess how the different approaches complement each other and to ensure a stable definition of a consistent set of lipoproteins. The results of detailed analysis of such proteins at the level of a single proteome are presented, corroborated and rationalized.
| Original language | English |
|---|---|
| Pages (from-to) | 1597-1613 |
| Number of pages | 17 |
| Journal | Proteomics |
| Volume | 4 |
| Issue number | 6 |
| DOIs | |
| State | Published - Jun 1 2004 |
| Externally published | Yes |
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Keywords
- Bacterial proteome
- Curated set
- Lipoprotein
- Signal prediction
ASJC Scopus subject areas
- Molecular Biology
- Genetics
Cite this
Fine-tuning the prediction of sequences cleaved by signal peptidase II : A curated set of proven and predicted lipoproteins of Escherichia coli K-12. / Gonnet, Pedro; Rudd, Kenneth E.; Lisacek, Frédérique.
In: Proteomics, Vol. 4, No. 6, 01.06.2004, p. 1597-1613.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Fine-tuning the prediction of sequences cleaved by signal peptidase II
T2 - A curated set of proven and predicted lipoproteins of Escherichia coli K-12
AU - Gonnet, Pedro
AU - Rudd, Kenneth E.
AU - Lisacek, Frédérique
PY - 2004/6/1
Y1 - 2004/6/1
N2 - A curated set of 81 proven and 44 predicted lipoproteins of Escherichia coli K-12 was defined with the combined use of a literature survey, a variety of predictive tools and human expertise. The well-documented Gram-negative proteome of E. coli K-12 was chosen to assess how the different approaches complement each other and to ensure a stable definition of a consistent set of lipoproteins. The results of detailed analysis of such proteins at the level of a single proteome are presented, corroborated and rationalized.
AB - A curated set of 81 proven and 44 predicted lipoproteins of Escherichia coli K-12 was defined with the combined use of a literature survey, a variety of predictive tools and human expertise. The well-documented Gram-negative proteome of E. coli K-12 was chosen to assess how the different approaches complement each other and to ensure a stable definition of a consistent set of lipoproteins. The results of detailed analysis of such proteins at the level of a single proteome are presented, corroborated and rationalized.
KW - Bacterial proteome
KW - Curated set
KW - Lipoprotein
KW - Signal prediction
UR - http://www.scopus.com/inward/record.url?scp=2942566270&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=2942566270&partnerID=8YFLogxK
U2 - 10.1002/pmic.200300749
DO - 10.1002/pmic.200300749
M3 - Article
C2 - 15174130
AN - SCOPUS:2942566270
VL - 4
SP - 1597
EP - 1613
JO - Proteomics
JF - Proteomics
SN - 1615-9853
IS - 6
ER -