Abstract
Lesions that contain abundant benign myoepithelial cells, including pleomorphic adenomas of salivary gland origin, may present a diagnostic challenge in fine-needle aspiration (FNA) specimens. Benign metastasizing pleomorphic adenoma is a rare neoplasm, in which the benign appearing pleomorphic adenoma, without any histological evidence of malignancy, metastasizes to distant sites including lung. In the absence of clinical history of a pre-existing myoepithelial neoplasm, the presence of myoepithelial cells in the lung or any other organs besides salivary glands may create diagnostic difficulty. Here we present the cytologic findings of such a metastatic tumor found in the lung FNA and pleural fluid specimens from a 64-year-old woman, with a history of local recurrent salivary gland pleomorphic adenomas, who presented with multiple bilateral pulmonary nodules and pleural effusion. The diagnosis of benign metastasizing pleomorphic adenoma was made based on clinical information and cytomorphology, and confirmed by immunocytochemistry.
| Original language | English |
|---|---|
| Pages (from-to) | 828-831 |
| Number of pages | 4 |
| Journal | Diagnostic Cytopathology |
| Volume | 37 |
| Issue number | 11 |
| DOIs | |
| State | Published - Nov 1 2009 |
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Keywords
- Benign metastasizing pleomorphic adenoma
- Cytology
- Fine-needle aspiration
- Lung
- Pleural fluid cytology
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Histology
Cite this
Fine-needle aspiration (FNA) and pleural fluid cytology diagnosis of benign metastasizing pleomorphic adenoma of the parotid gland in the lung : A case report and review of literature. / Yaxia, Zhang; Gomez-Fernandez, Carmen; Jorda, Merce; Ganjei-Azar, Parvin.
In: Diagnostic Cytopathology, Vol. 37, No. 11, 01.11.2009, p. 828-831.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Fine-needle aspiration (FNA) and pleural fluid cytology diagnosis of benign metastasizing pleomorphic adenoma of the parotid gland in the lung
T2 - A case report and review of literature
AU - Yaxia, Zhang
AU - Gomez-Fernandez, Carmen
AU - Jorda, Merce
AU - Ganjei-Azar, Parvin
PY - 2009/11/1
Y1 - 2009/11/1
N2 - Lesions that contain abundant benign myoepithelial cells, including pleomorphic adenomas of salivary gland origin, may present a diagnostic challenge in fine-needle aspiration (FNA) specimens. Benign metastasizing pleomorphic adenoma is a rare neoplasm, in which the benign appearing pleomorphic adenoma, without any histological evidence of malignancy, metastasizes to distant sites including lung. In the absence of clinical history of a pre-existing myoepithelial neoplasm, the presence of myoepithelial cells in the lung or any other organs besides salivary glands may create diagnostic difficulty. Here we present the cytologic findings of such a metastatic tumor found in the lung FNA and pleural fluid specimens from a 64-year-old woman, with a history of local recurrent salivary gland pleomorphic adenomas, who presented with multiple bilateral pulmonary nodules and pleural effusion. The diagnosis of benign metastasizing pleomorphic adenoma was made based on clinical information and cytomorphology, and confirmed by immunocytochemistry.
AB - Lesions that contain abundant benign myoepithelial cells, including pleomorphic adenomas of salivary gland origin, may present a diagnostic challenge in fine-needle aspiration (FNA) specimens. Benign metastasizing pleomorphic adenoma is a rare neoplasm, in which the benign appearing pleomorphic adenoma, without any histological evidence of malignancy, metastasizes to distant sites including lung. In the absence of clinical history of a pre-existing myoepithelial neoplasm, the presence of myoepithelial cells in the lung or any other organs besides salivary glands may create diagnostic difficulty. Here we present the cytologic findings of such a metastatic tumor found in the lung FNA and pleural fluid specimens from a 64-year-old woman, with a history of local recurrent salivary gland pleomorphic adenomas, who presented with multiple bilateral pulmonary nodules and pleural effusion. The diagnosis of benign metastasizing pleomorphic adenoma was made based on clinical information and cytomorphology, and confirmed by immunocytochemistry.
KW - Benign metastasizing pleomorphic adenoma
KW - Cytology
KW - Fine-needle aspiration
KW - Lung
KW - Pleural fluid cytology
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UR - http://www.scopus.com/inward/citedby.url?scp=70350345858&partnerID=8YFLogxK
U2 - 10.1002/dc.21123
DO - 10.1002/dc.21123
M3 - Article
C2 - 19582818
AN - SCOPUS:70350345858
VL - 37
SP - 828
EP - 831
JO - Diagnostic Cytopathology
JF - Diagnostic Cytopathology
SN - 8755-1039
IS - 11
ER -