Abstract
We studied twenty biopsies taken from fibrous papules which were located in the central part of the face. The lesions, which were characteristic histologically, did not contain S-100 protein within the stellate cells in the papillary dermis, nor was this substance found in mesenchymal cells with some features of nevus cells. In control studies, S-100 protein was found using an unlabeled antibody peroxidase-antiperoxidase technic within nevus cells composing junctional, intradermal, and compound nevi, Spitz nevi, and halo nevi. It therefore seems unlikely that fibrous papule represents a form of degenerated nevus as some investigators have proposed.
| Original language | English |
|---|---|
| Pages (from-to) | 360-362 |
| Number of pages | 3 |
| Journal | Journal of the American Academy of Dermatology |
| Volume | 9 |
| Issue number | 3 |
| State | Published - Jan 1 1983 |
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ASJC Scopus subject areas
- Dermatology
Cite this
Fibrous papule : An immunohistochemical study with an antibody to S-100 protein. / Spiegel, J.; Nadji, Mehrdad; Penneys, N. S.
In: Journal of the American Academy of Dermatology, Vol. 9, No. 3, 01.01.1983, p. 360-362.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Fibrous papule
T2 - An immunohistochemical study with an antibody to S-100 protein
AU - Spiegel, J.
AU - Nadji, Mehrdad
AU - Penneys, N. S.
PY - 1983/1/1
Y1 - 1983/1/1
N2 - We studied twenty biopsies taken from fibrous papules which were located in the central part of the face. The lesions, which were characteristic histologically, did not contain S-100 protein within the stellate cells in the papillary dermis, nor was this substance found in mesenchymal cells with some features of nevus cells. In control studies, S-100 protein was found using an unlabeled antibody peroxidase-antiperoxidase technic within nevus cells composing junctional, intradermal, and compound nevi, Spitz nevi, and halo nevi. It therefore seems unlikely that fibrous papule represents a form of degenerated nevus as some investigators have proposed.
AB - We studied twenty biopsies taken from fibrous papules which were located in the central part of the face. The lesions, which were characteristic histologically, did not contain S-100 protein within the stellate cells in the papillary dermis, nor was this substance found in mesenchymal cells with some features of nevus cells. In control studies, S-100 protein was found using an unlabeled antibody peroxidase-antiperoxidase technic within nevus cells composing junctional, intradermal, and compound nevi, Spitz nevi, and halo nevi. It therefore seems unlikely that fibrous papule represents a form of degenerated nevus as some investigators have proposed.
UR - http://www.scopus.com/inward/record.url?scp=0020523032&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0020523032&partnerID=8YFLogxK
M3 - Article
C2 - 6355208
AN - SCOPUS:0020523032
VL - 9
SP - 360
EP - 362
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
SN - 0190-9622
IS - 3
ER -