Fibrous papule: An immunohistochemical study with an antibody to S-100 protein

J. Spiegel, Mehrdad Nadji, N. S. Penneys

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

We studied twenty biopsies taken from fibrous papules which were located in the central part of the face. The lesions, which were characteristic histologically, did not contain S-100 protein within the stellate cells in the papillary dermis, nor was this substance found in mesenchymal cells with some features of nevus cells. In control studies, S-100 protein was found using an unlabeled antibody peroxidase-antiperoxidase technic within nevus cells composing junctional, intradermal, and compound nevi, Spitz nevi, and halo nevi. It therefore seems unlikely that fibrous papule represents a form of degenerated nevus as some investigators have proposed.

Original languageEnglish
Pages (from-to)360-362
Number of pages3
JournalJournal of the American Academy of Dermatology
Volume9
Issue number3
StatePublished - Jan 1 1983

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S100 Proteins
Nevus
Antibodies
Halo Nevi
Intradermal Nevus
Epithelioid and Spindle Cell Nevus
Dermis
Peroxidase
Research Personnel
Biopsy

ASJC Scopus subject areas

  • Dermatology

Cite this

Fibrous papule : An immunohistochemical study with an antibody to S-100 protein. / Spiegel, J.; Nadji, Mehrdad; Penneys, N. S.

In: Journal of the American Academy of Dermatology, Vol. 9, No. 3, 01.01.1983, p. 360-362.

Research output: Contribution to journalArticle

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