TY - JOUR
T1 - Fibrous papule
T2 - An immunohistochemical study with an antibody to S-100 protein
AU - Spiegel, Joan
AU - Nadji, Mehrdad
AU - Penneys, Neal S.
N1 - Funding Information:
From the Departments of Dermatology* and Pathology,** University of Miami School of Medicine. Supported by a grant from the National Institutes of Health, AM 28166, and by the Dermatology Foundation of Miami. Accepted for publication Jan. 7, 1983. Reprint requests to: Dr. Neal S. Penneys, Department of Dermatol-ogy 01-11), Box 016940, Miami, FL 33101.
PY - 1983
Y1 - 1983
N2 - We studied twenty biopsies taken from fibrous papules which were located in the central part of the face. The lesions, which were characteristic histologically, did not contain S-100 protein within the stellate cells in the papillary dermis, nor was this substance found in mesenchymal cells with some features of nevus cells. In control studies, S-100 protein was found using an unlabeled antibody peroxidase-antiperoxidase technic within nevus cells composing junctional, intradermal, and compound nevi, Spitz nevi, and halo nevi. It therefore seems unlikely that fibrous papule represents a form of degenerated nevus as some investigators have proposed.
AB - We studied twenty biopsies taken from fibrous papules which were located in the central part of the face. The lesions, which were characteristic histologically, did not contain S-100 protein within the stellate cells in the papillary dermis, nor was this substance found in mesenchymal cells with some features of nevus cells. In control studies, S-100 protein was found using an unlabeled antibody peroxidase-antiperoxidase technic within nevus cells composing junctional, intradermal, and compound nevi, Spitz nevi, and halo nevi. It therefore seems unlikely that fibrous papule represents a form of degenerated nevus as some investigators have proposed.
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U2 - 10.1016/S0190-9622(83)70142-8
DO - 10.1016/S0190-9622(83)70142-8
M3 - Article
C2 - 6355208
AN - SCOPUS:0020523032
VL - 9
SP - 360
EP - 362
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
SN - 0190-9622
IS - 3
ER -