Fetal tissue typing in anticipation of neonatal heart transplantation

Jerry M. Gilles; Gene Burkett; Richard A. Perryman; Peter L. Ferrer

doi:10.1016/S0029-7844(97)00480-8

Fetal tissue typing in anticipation of neonatal heart transplantation

Jerry M. Gilles, Gene Burkett, Richard A. Perryman, Peter L. Ferrer

Obstetrics & Gynecology

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Background: Hypoplastic left heart syndrome is among the most common major congenital cardiac anomalies. Fetuses with this anomaly survive but require either reconstructive surgery or heart transplantation postnatally. Case: A woman whose fetus was diagnosed with hypoplastic left heart syndrome underwent funipuncture for fetal tissue typing. The fetus then was listed for heart transplantation. Once an ABO-compatible donor heart was procured, the fetus was delivered and immediately underwent transplantation. Conclusion: In candidates for neonatal heart transplantation, fetal tissue typing allows the search for an ABO-compatible donor heart to begin earlier. This approach minimizes the morbidity associated with postnatal waiting and allows transplantation to take place while the neonate is less immunocompetent.

Original language	English (US)
Pages (from-to)	823-825
Number of pages	3
Journal	Obstetrics and gynecology
Volume	91
Issue number	5 II SUPPL.
DOIs	https://doi.org/10.1016/S0029-7844(97)00480-8
State	Published - May 1998

ASJC Scopus subject areas

Obstetrics and Gynecology

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abstract = "Background: Hypoplastic left heart syndrome is among the most common major congenital cardiac anomalies. Fetuses with this anomaly survive but require either reconstructive surgery or heart transplantation postnatally. Case: A woman whose fetus was diagnosed with hypoplastic left heart syndrome underwent funipuncture for fetal tissue typing. The fetus then was listed for heart transplantation. Once an ABO-compatible donor heart was procured, the fetus was delivered and immediately underwent transplantation. Conclusion: In candidates for neonatal heart transplantation, fetal tissue typing allows the search for an ABO-compatible donor heart to begin earlier. This approach minimizes the morbidity associated with postnatal waiting and allows transplantation to take place while the neonate is less immunocompetent.",

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AU - Burkett, Gene

AU - Perryman, Richard A.

AU - Ferrer, Peter L.

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N2 - Background: Hypoplastic left heart syndrome is among the most common major congenital cardiac anomalies. Fetuses with this anomaly survive but require either reconstructive surgery or heart transplantation postnatally. Case: A woman whose fetus was diagnosed with hypoplastic left heart syndrome underwent funipuncture for fetal tissue typing. The fetus then was listed for heart transplantation. Once an ABO-compatible donor heart was procured, the fetus was delivered and immediately underwent transplantation. Conclusion: In candidates for neonatal heart transplantation, fetal tissue typing allows the search for an ABO-compatible donor heart to begin earlier. This approach minimizes the morbidity associated with postnatal waiting and allows transplantation to take place while the neonate is less immunocompetent.

AB - Background: Hypoplastic left heart syndrome is among the most common major congenital cardiac anomalies. Fetuses with this anomaly survive but require either reconstructive surgery or heart transplantation postnatally. Case: A woman whose fetus was diagnosed with hypoplastic left heart syndrome underwent funipuncture for fetal tissue typing. The fetus then was listed for heart transplantation. Once an ABO-compatible donor heart was procured, the fetus was delivered and immediately underwent transplantation. Conclusion: In candidates for neonatal heart transplantation, fetal tissue typing allows the search for an ABO-compatible donor heart to begin earlier. This approach minimizes the morbidity associated with postnatal waiting and allows transplantation to take place while the neonate is less immunocompetent.

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Fetal tissue typing in anticipation of neonatal heart transplantation

Abstract

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