Fertility and pregnancy after operation for a prolactinoma

AMANDA M. RICHARDS, M. R.R. BULLOCK, G. M. TEASDALE, J. A. THOMSON, M. I. KHAN

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Pituitary exploration was performed in 40 women with hyperprolactinaemic infertility and a prolactinoma was found in 37. After operation 26 (65%) of the 40 patients had a normal serum prolactin concentration; 31 women have so far had 49 pregnancies; in seven of these patients bromocriptine therapy was used after surgery. Eight of the remaining nine women were shown to be ovulating, but four of these subsequently decided not to attempt a pregnancy. The course and outcome of the 49 pregnancies were similar to those in normal women and no visual or endocrine complications occurred. Surgical removal of a prolactinoma often restores fertility, and may secure a safer pregnancy.

Original languageEnglish (US)
Pages (from-to)495-502
Number of pages8
JournalBJOG: An International Journal of Obstetrics & Gynaecology
Volume93
Issue number4
DOIs
StatePublished - Apr 1986

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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