Femtosecond laser corneal refractive surgery

Ron Kurtz, Greg Spooner, Karin Sletten, Kim Yen, Samir Sayegh, Frieder Loesel, Christopher Horvath, Hsia Hua Liu, Victor Elner, Delia Cabrera DeBuc, Marie Helene Meunier, Zachary Sacks, Tibor Juhasz

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Abstract

We evaluated the efficacy, safety, and stability of femtosecond laser intrastromal refractive procedures in ex vivo and in vivo models. When compared with longer pulsewidth nanosecond or picosecond laser pulses, femtosecond laser-tissue interactions are characterized by significantly smaller and more deterministic photodisruptive energy thresholds, as well as reduced shock waves and smaller cavitation bubbles. We utilized a highly reliable, all-solid-state femtosecond laser system for all studies to demonstrate clinical practicality. Contiguous tissue effects were achieved by scanning a 5 μm focused laser spot below the corneal surface at pulse energies of approximately 2-4 microjoules. A variety of scanning patterns was used to perform three prototype procedures in animal eyes; corneal flap cutting, keratomileusis, and intrastromal vision correction. Superior dissection and surface quality results were obtained for lamellar procedures (corneal flap cutting and keratomileusis). Preliminary in vivo evaluation of intrastromal vision correction in a rabbit model revealed consistent and stable pachymetry changes, without significant inflammation or loss of corneal transparency. We conclude that femtosecond laser technology may be able to perform a variety of corneal refractive procedures with high precision, offering advantages over current mechanical and laser devices and techniques.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
PublisherSociety of Photo-Optical Instrumentation Engineers
Pages209-219
Number of pages11
Volume3591
StatePublished - 1999
Externally publishedYes
EventProceedings of the 1999 Ophthalmic Technologies IX - San Jose, CA, USA
Duration: Jan 23 1999Jan 25 1999

Other

OtherProceedings of the 1999 Ophthalmic Technologies IX
CitySan Jose, CA, USA
Period1/23/991/25/99

Fingerprint

Ultrashort pulses
surgery
Surgery
Vision aids
lasers
Laser tissue interaction
Scanning
Dissection
Lasers
Bubbles (in fluids)
Cavitation
Shock waves
Transparency
Surface properties
mechanical devices
Laser pulses
dissection
Animals
scanning
rabbits

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Kurtz, R., Spooner, G., Sletten, K., Yen, K., Sayegh, S., Loesel, F., ... Juhasz, T. (1999). Femtosecond laser corneal refractive surgery. In Proceedings of SPIE - The International Society for Optical Engineering (Vol. 3591, pp. 209-219). Society of Photo-Optical Instrumentation Engineers.

Femtosecond laser corneal refractive surgery. / Kurtz, Ron; Spooner, Greg; Sletten, Karin; Yen, Kim; Sayegh, Samir; Loesel, Frieder; Horvath, Christopher; Liu, Hsia Hua; Elner, Victor; Cabrera DeBuc, Delia; Meunier, Marie Helene; Sacks, Zachary; Juhasz, Tibor.

Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3591 Society of Photo-Optical Instrumentation Engineers, 1999. p. 209-219.

Research output: Chapter in Book/Report/Conference proceedingChapter

Kurtz, R, Spooner, G, Sletten, K, Yen, K, Sayegh, S, Loesel, F, Horvath, C, Liu, HH, Elner, V, Cabrera DeBuc, D, Meunier, MH, Sacks, Z & Juhasz, T 1999, Femtosecond laser corneal refractive surgery. in Proceedings of SPIE - The International Society for Optical Engineering. vol. 3591, Society of Photo-Optical Instrumentation Engineers, pp. 209-219, Proceedings of the 1999 Ophthalmic Technologies IX, San Jose, CA, USA, 1/23/99.
Kurtz R, Spooner G, Sletten K, Yen K, Sayegh S, Loesel F et al. Femtosecond laser corneal refractive surgery. In Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3591. Society of Photo-Optical Instrumentation Engineers. 1999. p. 209-219
Kurtz, Ron ; Spooner, Greg ; Sletten, Karin ; Yen, Kim ; Sayegh, Samir ; Loesel, Frieder ; Horvath, Christopher ; Liu, Hsia Hua ; Elner, Victor ; Cabrera DeBuc, Delia ; Meunier, Marie Helene ; Sacks, Zachary ; Juhasz, Tibor. / Femtosecond laser corneal refractive surgery. Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3591 Society of Photo-Optical Instrumentation Engineers, 1999. pp. 209-219
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AU - Horvath, Christopher

AU - Liu, Hsia Hua

AU - Elner, Victor

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