Femtosecond Laser-Assisted Sutureless Anterior Lamellar Keratoplasty

Sonia H Yoo, George D. Kymionis, Aaleya Koreishi, Takeshi Ide, David Goldman, Carol Karp, Terrence O'Brien, William W Culbertson, Eduardo C Alfonso

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Abstract

Purpose: To report the technique and small case series results of femtosecond laser-assisted sutureless anterior lamellar keratoplasty (FALK) for anterior corneal pathology. Design: Retrospective, noncomparative, interventional case series. Participants: Twelve consecutive eyes from 12 patients with anterior corneal scarring. Intervention: Femtosecond laser-assisted sutureless anterior lamellar keratoplasty. Main Outcome Measures: Measured parameters included femtosecond laser settings, technique, uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), and complications. Results: Mean follow-up was 12.7 months (range, 6-24). No intraoperative complications were found. Uncorrected visual acuity (VA) improved in 7 eyes (58.3%) compared with preoperative VA. The mean difference between preoperative and postoperative UCVAs was a gain of 2.5 lines (range, unchanged-7 lines). Best-corrected VA was unchanged or improved in all eyes compared with preoperative levels. The mean difference between preoperative and postoperative BCVAs was a gain of 3.8 lines (range, unchanged-8 lines). In 2 eyes, adjuvant surgical procedures were performed (one treated with phototherapeutic keratectomy and the other with photorefractive keratectomy). Six patients (50%) developed dry eye after FALK, which improved during the follow-up period. No graft rejection, infection, or epithelial ingrowth was found in this series of patients. Conclusions: Femtosecond laser-assisted sutureless anterior lamellar keratoplasty could improve UCVA and BCVA in patients with anterior corneal pathology.

Original languageEnglish
JournalOphthalmology
Volume115
Issue number8
DOIs
StatePublished - Aug 1 2008

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Corneal Transplantation
Visual Acuity
Lasers
Pathology
Photorefractive Keratectomy
Intraoperative Complications
Graft Rejection
Cicatrix
Outcome Assessment (Health Care)
Infection

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Femtosecond Laser-Assisted Sutureless Anterior Lamellar Keratoplasty. / Yoo, Sonia H; Kymionis, George D.; Koreishi, Aaleya; Ide, Takeshi; Goldman, David; Karp, Carol; O'Brien, Terrence; Culbertson, William W; Alfonso, Eduardo C.

In: Ophthalmology, Vol. 115, No. 8, 01.08.2008.

Research output: Contribution to journalArticle

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abstract = "Purpose: To report the technique and small case series results of femtosecond laser-assisted sutureless anterior lamellar keratoplasty (FALK) for anterior corneal pathology. Design: Retrospective, noncomparative, interventional case series. Participants: Twelve consecutive eyes from 12 patients with anterior corneal scarring. Intervention: Femtosecond laser-assisted sutureless anterior lamellar keratoplasty. Main Outcome Measures: Measured parameters included femtosecond laser settings, technique, uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), and complications. Results: Mean follow-up was 12.7 months (range, 6-24). No intraoperative complications were found. Uncorrected visual acuity (VA) improved in 7 eyes (58.3{\%}) compared with preoperative VA. The mean difference between preoperative and postoperative UCVAs was a gain of 2.5 lines (range, unchanged-7 lines). Best-corrected VA was unchanged or improved in all eyes compared with preoperative levels. The mean difference between preoperative and postoperative BCVAs was a gain of 3.8 lines (range, unchanged-8 lines). In 2 eyes, adjuvant surgical procedures were performed (one treated with phototherapeutic keratectomy and the other with photorefractive keratectomy). Six patients (50{\%}) developed dry eye after FALK, which improved during the follow-up period. No graft rejection, infection, or epithelial ingrowth was found in this series of patients. Conclusions: Femtosecond laser-assisted sutureless anterior lamellar keratoplasty could improve UCVA and BCVA in patients with anterior corneal pathology.",
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AU - Goldman, David

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N2 - Purpose: To report the technique and small case series results of femtosecond laser-assisted sutureless anterior lamellar keratoplasty (FALK) for anterior corneal pathology. Design: Retrospective, noncomparative, interventional case series. Participants: Twelve consecutive eyes from 12 patients with anterior corneal scarring. Intervention: Femtosecond laser-assisted sutureless anterior lamellar keratoplasty. Main Outcome Measures: Measured parameters included femtosecond laser settings, technique, uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), and complications. Results: Mean follow-up was 12.7 months (range, 6-24). No intraoperative complications were found. Uncorrected visual acuity (VA) improved in 7 eyes (58.3%) compared with preoperative VA. The mean difference between preoperative and postoperative UCVAs was a gain of 2.5 lines (range, unchanged-7 lines). Best-corrected VA was unchanged or improved in all eyes compared with preoperative levels. The mean difference between preoperative and postoperative BCVAs was a gain of 3.8 lines (range, unchanged-8 lines). In 2 eyes, adjuvant surgical procedures were performed (one treated with phototherapeutic keratectomy and the other with photorefractive keratectomy). Six patients (50%) developed dry eye after FALK, which improved during the follow-up period. No graft rejection, infection, or epithelial ingrowth was found in this series of patients. Conclusions: Femtosecond laser-assisted sutureless anterior lamellar keratoplasty could improve UCVA and BCVA in patients with anterior corneal pathology.

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