Features of an autoimmune process in mid-dermal elastolysis

Robert Kirsner, V. Falanga

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Mid-dermal elastolysis is a rare disorder that is manifested clinically by wrinkling and histologically by the selective absence of elastic fibers in the mid dermis. We describe a young woman who developed abnormal wrinkling after augmentation mammoplasty with silicone implants. Histologic examination confirmed the diagnosis of mid-dermal elastolysis. In addition, a positive antinuclear antibody titer and a false-positive Lyme titer were subsequently detected. In a previously reported case a patient who had mid-dermal elastolysis also had an unusual false-positive pattern for Lyme disease. Silicone mammoplasty has been associated with connective tissue diseases. This report adds mid-dermal elastolysis to the list of diseases associated with augmentation mammoplasty and, along with the presence of autoantibodies, supports autoimmune involvement in mid-dermal elastolysis.

Original languageEnglish
Pages (from-to)832-834
Number of pages3
JournalJournal of the American Academy of Dermatology
Volume27
Issue number5 II
StatePublished - Jan 1 1992

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Mammaplasty
Skin
Silicones
Connective Tissue Diseases
Elastic Tissue
Lyme Disease
Antinuclear Antibodies
Dermis
Autoantibodies

ASJC Scopus subject areas

  • Dermatology

Cite this

Features of an autoimmune process in mid-dermal elastolysis. / Kirsner, Robert; Falanga, V.

In: Journal of the American Academy of Dermatology, Vol. 27, No. 5 II, 01.01.1992, p. 832-834.

Research output: Contribution to journalArticle

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