Feasibility study of ultrasonic fatty liver biopsy: Texture vs. attenuation and backscatter

Diana Gaitini; Yaacov Baruch; Eduard Ghersin; Ella Veitsman; Hedvika Kerner; Bruria Shalem; Geva Yaniv; Chen Sarfaty; Haim Azhari

doi:10.1016/j.ultrasmedbio.2004.08.001

Feasibility study of ultrasonic fatty liver biopsy: Texture vs. attenuation and backscatter

Diana Gaitini, Yaacov Baruch, Eduard Ghersin, Ella Veitsman, Hedvika Kerner, Bruria Shalem, Geva Yaniv, Chen Sarfaty, Haim Azhari

Research output: Contribution to journal › Article › peer-review

72 Scopus citations

Abstract

The objective of this study was to compare textural to attenuation/ backscatter indices of fatty liver correlated to histology to suggest the better approach for an objective noninvasive ultrasonic "biopsy". Forty-four patients with severe steatosis by histopathology were selected for this study. Ten patients had "pure" fatty liver and 34 had in addition fibrosis and/or inflammation. Ultrasonic images were acquired before needle insertion. The ROI used for biopsy was marked on the ultrasonic image and characterized by three attenuation/backscatter and 18 textural related indices. Statistical analysis was performed using logistic regression. Twenty-one healthy subjects served as control. The attenuation/backscatter indices were superior to textural indices in differentiating between the categories studied. Pure fatty livers could be reliably identified (AUC = 1, SE = 0). Among the 18 textural indices, "co-occurrences sum entropy" and "co-occurrences entropy" presented the best results. Attenuation/backscatter based indices appear to have better potential than the textural based indices. (E-mail: D_Gaitini@Rambam. Health.Gov.IL).

Original language	English (US)
Pages (from-to)	1321-1327
Number of pages	7
Journal	Ultrasound in Medicine and Biology
Volume	30
Issue number	10
DOIs	https://doi.org/10.1016/j.ultrasmedbio.2004.08.001
State	Published - Oct 2004
Externally published	Yes

Keywords

Acoustic attenuation
Biopsy
Diffuse liver disease
Histology
Needle biopsy
Steatosis
Texture
Ultrasound

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

Access to Document

10.1016/j.ultrasmedbio.2004.08.001

Cite this

Feasibility study of ultrasonic fatty liver biopsy : Texture vs. attenuation and backscatter. / Gaitini, Diana; Baruch, Yaacov; Ghersin, Eduard; Veitsman, Ella; Kerner, Hedvika; Shalem, Bruria; Yaniv, Geva; Sarfaty, Chen; Azhari, Haim.

In: Ultrasound in Medicine and Biology, Vol. 30, No. 10, 10.2004, p. 1321-1327.

Research output: Contribution to journal › Article › peer-review

@article{3b59f34342bc4c759be636cfebd1f258,

title = "Feasibility study of ultrasonic fatty liver biopsy: Texture vs. attenuation and backscatter",

abstract = "The objective of this study was to compare textural to attenuation/ backscatter indices of fatty liver correlated to histology to suggest the better approach for an objective noninvasive ultrasonic {"}biopsy{"}. Forty-four patients with severe steatosis by histopathology were selected for this study. Ten patients had {"}pure{"} fatty liver and 34 had in addition fibrosis and/or inflammation. Ultrasonic images were acquired before needle insertion. The ROI used for biopsy was marked on the ultrasonic image and characterized by three attenuation/backscatter and 18 textural related indices. Statistical analysis was performed using logistic regression. Twenty-one healthy subjects served as control. The attenuation/backscatter indices were superior to textural indices in differentiating between the categories studied. Pure fatty livers could be reliably identified (AUC = 1, SE = 0). Among the 18 textural indices, {"}co-occurrences sum entropy{"} and {"}co-occurrences entropy{"} presented the best results. Attenuation/backscatter based indices appear to have better potential than the textural based indices. (E-mail: D_Gaitini@Rambam. Health.Gov.IL).",

keywords = "Acoustic attenuation, Biopsy, Diffuse liver disease, Histology, Needle biopsy, Steatosis, Texture, Ultrasound",

author = "Diana Gaitini and Yaacov Baruch and Eduard Ghersin and Ella Veitsman and Hedvika Kerner and Bruria Shalem and Geva Yaniv and Chen Sarfaty and Haim Azhari",

year = "2004",

month = oct,

doi = "10.1016/j.ultrasmedbio.2004.08.001",

language = "English (US)",

volume = "30",

pages = "1321--1327",

journal = "Ultrasound in Medicine and Biology",

issn = "0301-5629",

publisher = "Elsevier USA",

number = "10",

}

TY - JOUR

T1 - Feasibility study of ultrasonic fatty liver biopsy

T2 - Texture vs. attenuation and backscatter

AU - Gaitini, Diana

AU - Baruch, Yaacov

AU - Ghersin, Eduard

AU - Veitsman, Ella

AU - Kerner, Hedvika

AU - Shalem, Bruria

AU - Yaniv, Geva

AU - Sarfaty, Chen

AU - Azhari, Haim

PY - 2004/10

Y1 - 2004/10

N2 - The objective of this study was to compare textural to attenuation/ backscatter indices of fatty liver correlated to histology to suggest the better approach for an objective noninvasive ultrasonic "biopsy". Forty-four patients with severe steatosis by histopathology were selected for this study. Ten patients had "pure" fatty liver and 34 had in addition fibrosis and/or inflammation. Ultrasonic images were acquired before needle insertion. The ROI used for biopsy was marked on the ultrasonic image and characterized by three attenuation/backscatter and 18 textural related indices. Statistical analysis was performed using logistic regression. Twenty-one healthy subjects served as control. The attenuation/backscatter indices were superior to textural indices in differentiating between the categories studied. Pure fatty livers could be reliably identified (AUC = 1, SE = 0). Among the 18 textural indices, "co-occurrences sum entropy" and "co-occurrences entropy" presented the best results. Attenuation/backscatter based indices appear to have better potential than the textural based indices. (E-mail: D_Gaitini@Rambam. Health.Gov.IL).

AB - The objective of this study was to compare textural to attenuation/ backscatter indices of fatty liver correlated to histology to suggest the better approach for an objective noninvasive ultrasonic "biopsy". Forty-four patients with severe steatosis by histopathology were selected for this study. Ten patients had "pure" fatty liver and 34 had in addition fibrosis and/or inflammation. Ultrasonic images were acquired before needle insertion. The ROI used for biopsy was marked on the ultrasonic image and characterized by three attenuation/backscatter and 18 textural related indices. Statistical analysis was performed using logistic regression. Twenty-one healthy subjects served as control. The attenuation/backscatter indices were superior to textural indices in differentiating between the categories studied. Pure fatty livers could be reliably identified (AUC = 1, SE = 0). Among the 18 textural indices, "co-occurrences sum entropy" and "co-occurrences entropy" presented the best results. Attenuation/backscatter based indices appear to have better potential than the textural based indices. (E-mail: D_Gaitini@Rambam. Health.Gov.IL).

KW - Acoustic attenuation

KW - Biopsy

KW - Diffuse liver disease

KW - Histology

KW - Needle biopsy

KW - Steatosis

KW - Texture

KW - Ultrasound

UR - http://www.scopus.com/inward/record.url?scp=9644256057&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=9644256057&partnerID=8YFLogxK

U2 - 10.1016/j.ultrasmedbio.2004.08.001

DO - 10.1016/j.ultrasmedbio.2004.08.001

M3 - Article

C2 - 15582231

AN - SCOPUS:9644256057

VL - 30

SP - 1321

EP - 1327

JO - Ultrasound in Medicine and Biology

JF - Ultrasound in Medicine and Biology

SN - 0301-5629

IS - 10

ER -

Feasibility study of ultrasonic fatty liver biopsy: Texture vs. attenuation and backscatter

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this