Feasibility study of ultrasonic fatty liver biopsy: Texture vs. attenuation and backscatter

Diana Gaitini; Yaacov Baruch; Eduard Ghersin; Ella Veitsman; Hedvika Kerner; Bruria Shalem; Geva Yaniv; Chen Sarfaty; Haim Azhari

doi:10.1016/j.ultrasmedbio.2004.08.001

Feasibility study of ultrasonic fatty liver biopsy: Texture vs. attenuation and backscatter

Diana Gaitini, Yaacov Baruch, Eduard Ghersin, Ella Veitsman, Hedvika Kerner, Bruria Shalem, Geva Yaniv, Chen Sarfaty, Haim Azhari

Radiology

Research output: Contribution to journal › Article

68 Scopus citations

Abstract

The objective of this study was to compare textural to attenuation/ backscatter indices of fatty liver correlated to histology to suggest the better approach for an objective noninvasive ultrasonic "biopsy". Forty-four patients with severe steatosis by histopathology were selected for this study. Ten patients had "pure" fatty liver and 34 had in addition fibrosis and/or inflammation. Ultrasonic images were acquired before needle insertion. The ROI used for biopsy was marked on the ultrasonic image and characterized by three attenuation/backscatter and 18 textural related indices. Statistical analysis was performed using logistic regression. Twenty-one healthy subjects served as control. The attenuation/backscatter indices were superior to textural indices in differentiating between the categories studied. Pure fatty livers could be reliably identified (AUC = 1, SE = 0). Among the 18 textural indices, "co-occurrences sum entropy" and "co-occurrences entropy" presented the best results. Attenuation/backscatter based indices appear to have better potential than the textural based indices. (E-mail: D_Gaitini@Rambam. Health.Gov.IL).

Original language	English (US)
Pages (from-to)	1321-1327
Number of pages	7
Journal	Ultrasound in Medicine and Biology
Volume	30
Issue number	10
DOIs	https://doi.org/10.1016/j.ultrasmedbio.2004.08.001
State	Published - Oct 2004

Keywords

Acoustic attenuation
Biopsy
Diffuse liver disease
Histology
Needle biopsy
Steatosis
Texture
Ultrasound

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1016/j.ultrasmedbio.2004.08.001

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Gaitini, D., Baruch, Y., Ghersin, E., Veitsman, E., Kerner, H., Shalem, B., Yaniv, G., Sarfaty, C., & Azhari, H. (2004). Feasibility study of ultrasonic fatty liver biopsy: Texture vs. attenuation and backscatter. Ultrasound in Medicine and Biology, 30(10), 1321-1327. https://doi.org/10.1016/j.ultrasmedbio.2004.08.001

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abstract = "The objective of this study was to compare textural to attenuation/ backscatter indices of fatty liver correlated to histology to suggest the better approach for an objective noninvasive ultrasonic {"}biopsy{"}. Forty-four patients with severe steatosis by histopathology were selected for this study. Ten patients had {"}pure{"} fatty liver and 34 had in addition fibrosis and/or inflammation. Ultrasonic images were acquired before needle insertion. The ROI used for biopsy was marked on the ultrasonic image and characterized by three attenuation/backscatter and 18 textural related indices. Statistical analysis was performed using logistic regression. Twenty-one healthy subjects served as control. The attenuation/backscatter indices were superior to textural indices in differentiating between the categories studied. Pure fatty livers could be reliably identified (AUC = 1, SE = 0). Among the 18 textural indices, {"}co-occurrences sum entropy{"} and {"}co-occurrences entropy{"} presented the best results. Attenuation/backscatter based indices appear to have better potential than the textural based indices. (E-mail: D_Gaitini@Rambam. Health.Gov.IL).",

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