Feasibility study of ultrasonic fatty liver biopsy: Texture vs. attenuation and backscatter

Diana Gaitini, Yaacov Baruch, Eduard Ghersin, Ella Veitsman, Hedvika Kerner, Bruria Shalem, Geva Yaniv, Chen Sarfaty, Haim Azhari

Research output: Contribution to journalArticle

67 Citations (Scopus)

Abstract

The objective of this study was to compare textural to attenuation/ backscatter indices of fatty liver correlated to histology to suggest the better approach for an objective noninvasive ultrasonic "biopsy". Forty-four patients with severe steatosis by histopathology were selected for this study. Ten patients had "pure" fatty liver and 34 had in addition fibrosis and/or inflammation. Ultrasonic images were acquired before needle insertion. The ROI used for biopsy was marked on the ultrasonic image and characterized by three attenuation/backscatter and 18 textural related indices. Statistical analysis was performed using logistic regression. Twenty-one healthy subjects served as control. The attenuation/backscatter indices were superior to textural indices in differentiating between the categories studied. Pure fatty livers could be reliably identified (AUC = 1, SE = 0). Among the 18 textural indices, "co-occurrences sum entropy" and "co-occurrences entropy" presented the best results. Attenuation/backscatter based indices appear to have better potential than the textural based indices. (E-mail: D_Gaitini@Rambam. Health.Gov.IL).

Original languageEnglish
Pages (from-to)1321-1327
Number of pages7
JournalUltrasound in Medicine and Biology
Volume30
Issue number10
DOIs
StatePublished - Oct 1 2004
Externally publishedYes

Fingerprint

Feasibility Studies
Fatty Liver
liver
Ultrasonics
textures
ultrasonics
attenuation
Entropy
Biopsy
Area Under Curve
Needles
Histology
Healthy Volunteers
Fibrosis
Logistic Models
Inflammation
occurrences
entropy
Health
fibrosis

Keywords

  • Acoustic attenuation
  • Biopsy
  • Diffuse liver disease
  • Histology
  • Needle biopsy
  • Steatosis
  • Texture
  • Ultrasound

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Feasibility study of ultrasonic fatty liver biopsy : Texture vs. attenuation and backscatter. / Gaitini, Diana; Baruch, Yaacov; Ghersin, Eduard; Veitsman, Ella; Kerner, Hedvika; Shalem, Bruria; Yaniv, Geva; Sarfaty, Chen; Azhari, Haim.

In: Ultrasound in Medicine and Biology, Vol. 30, No. 10, 01.10.2004, p. 1321-1327.

Research output: Contribution to journalArticle

Gaitini, D, Baruch, Y, Ghersin, E, Veitsman, E, Kerner, H, Shalem, B, Yaniv, G, Sarfaty, C & Azhari, H 2004, 'Feasibility study of ultrasonic fatty liver biopsy: Texture vs. attenuation and backscatter', Ultrasound in Medicine and Biology, vol. 30, no. 10, pp. 1321-1327. https://doi.org/10.1016/j.ultrasmedbio.2004.08.001
Gaitini, Diana ; Baruch, Yaacov ; Ghersin, Eduard ; Veitsman, Ella ; Kerner, Hedvika ; Shalem, Bruria ; Yaniv, Geva ; Sarfaty, Chen ; Azhari, Haim. / Feasibility study of ultrasonic fatty liver biopsy : Texture vs. attenuation and backscatter. In: Ultrasound in Medicine and Biology. 2004 ; Vol. 30, No. 10. pp. 1321-1327.
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