Fc and C3b receptors on pulmonary endothelial cells: Induction by injury

Una S. Ryan, Duane R. Schultz, James W. Ryan

Research output: Contribution to journalArticle

66 Scopus citations

Abstract

Receptors for the activated third component of complement and for the Fc portion of immunoglobulin G are not expressed by apparently normal bovine pulmonary endothelial cells, but are expressed when the cells are exposed to white cell lysates or are infected with influenza or cytomegalovirus. The unmasking of these latent receptors may contribute to the pulmonary inflammatory response characteristic of, for example, anaphylaxis and to those lung diseases characterized by the deposition of immune complexes.

Original languageEnglish (US)
Pages (from-to)557-558
Number of pages2
JournalScience
Volume214
Issue number4520
DOIs
StatePublished - Jan 1 1981

ASJC Scopus subject areas

  • General

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