Fatal herpes simplex virus type 2 hepatitis in a heart transplant recipient: A case report and review of the literature

P. Pietrucha-Dilanchian, T. Tanawuttiwat, L. Abbo, A. Regatieri, S. Chaparro, P. Ruiz, M. I. Morris

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Herpes simplex virus (HSV) hepatitis is often unrecognized clinically with most untreated cases diagnosed postmortem. HSV hepatitis has been reported in solid organ transplant (SOT) recipients, mostly in kidney and liver transplants, and rarely in heart transplant recipients. We describe a fatal case of community-acquired HSV-2 hepatitis in a 24-year-old heart transplant recipient occurring 3 years after transplant. We also review the literature summarizing HSV hepatitis and the potential role of quantitative HSV polymerase chain reaction monitoring in the SOT population.

Original languageEnglish (US)
Pages (from-to)E87-E96
JournalTransplant Infectious Disease
Volume15
Issue number3
DOIs
StatePublished - Jun 1 2013

Keywords

  • Heart transplant
  • Hepatitis
  • Herpes simplex virus
  • Solid organ transplant

ASJC Scopus subject areas

  • Transplantation
  • Infectious Diseases

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