Familial presentation of intracranial occlusive arteriopathy and ischemic stroke in patients with graves' hyperthyroidism

Priyank Khandelwal, Nirav Shah, Tannvi Prakash, Gustavo Ortiz

Research output: Contribution to journalArticle


Background: The comorbidity of intracranial occlusive arteriopathy and Graves' disease (GD) is increasingly being reported. Methods: We describe two patients (mother and daughter) with GD, intracranial occlusive arteriopathy, and ischemic strokes. Results: Both patients were thyrotoxic at the time of the ischemic event, and the intracranial arterial stenosis was progressive while in thyrotoxic state. In one of the cases, there was no further progression of the disease after 1 year of follow up, once hyperthyroidism was well controlled. Conclusion: To the best of our knowledge, this is the first report of familial presentation of moyamoya-like vasculopathy in patients with GD in Latin population.

Original languageEnglish (US)
Pages (from-to)89-91
Number of pages3
JournalUS Endocrinology
Issue number2
StatePublished - 2015



  • Graves' disease
  • Intracranial stenosis
  • Ischemic stroke
  • Moyamoya syndrome
  • Stroke in young adults

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism

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