Familial predisposition for herniation of a lumbar disc in patients who are less than twenty-one years old

G. P. Varlotta, M. D. Brown, J. L. Kelsey, A. L. Golden

Research output: Contribution to journalArticlepeer-review

109 Scopus citations

Abstract

The parents of sixty-three patients who were less than twenty-one years old and who had operatively confirmed herniation of a lumbar disc were interviewed regarding a history of severe back pain, sciatica, and herniated disc, to determine whether aggregation of herniation of a lumbar disc occurs in families of patients in this young age-group. The parents of sixty-three additional patients who had a non-spinal orthopaedic diagnosis (control group) were matched for age and sex with the study group and were given the same interview. Of the patients who had herniation of a lumbar disc and were less than twenty-one years old, 32 per cent had a positive family history for that lesion compared with 7 per cent of the control group. The relative risk of development of herniation of a lumbar disc before the age of twenty-one years is estimated to be approximately five times greater in patients who have a positive family history. The results indicate a familial basis for herniation of a lumbar disc in patients who are less than twenty-one years old.

Original languageEnglish (US)
Pages (from-to)124-128
Number of pages5
JournalJournal of Bone and Joint Surgery - Series A
Volume73
Issue number1
DOIs
StatePublished - Jan 1 1991
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

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