Familial aggregation of total cholesterol, high density lipoprotein cholesterol and total triglyceride levels in plasma

Jay M. Sosenko, Jan L. Breslow, R. Curtis Ellison, Olli S. Miettinen

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

Familial aggregation of plasma cholesterol, high density lipoprotein cholesterol (HDL-C), and triglyceride was assessed on the basis of 139 white families consisting of the parents and one child, 16-18 years of age, drawn from families who had previously participated in the Collaborative Perinatal Health Study of Boston Hospital for Women in 1959-1968. The level of these lipids in the child was highly correlated with the average parental value for the respective lipids (cholesterol r = 0.43, HDL-C r = 0.36, triglyceride r = 0.42), with p<0.001 for each). These correlations could not be explained by ponderosity. Parental values were not mutually correlated.

Original languageEnglish (US)
Pages (from-to)656-660
Number of pages5
JournalAmerican journal of epidemiology
Volume112
Issue number5
DOIs
StatePublished - Nov 1980
Externally publishedYes

Keywords

  • Cholesterol
  • HDL
  • Lipoproteins
  • Triglycerides

ASJC Scopus subject areas

  • Epidemiology

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