Abstract
Four women 5 to 8 weeks into pregnancy, scheduled for therapeutic abortions, were given an analog of gonadotropin-releasing hormone, D-tryptophan-6-LHRH, in an effort to interrupt pregnancy. The treatment consisted of 100 μg injections, given twice daily for 5 to 10 days. No decline in serum β-hCG or progesterone was noted, and menstrual extraction was needed in all women for pregnancy interruption. These data indicate that D-Trp-6-LHRH is not effective as an abortifacient in established pregnancy.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 241-242 |
| Number of pages | 2 |
| Journal | Fertility and Sterility |
| Volume | 36 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jan 1 1981 |
| Externally published | Yes |
ASJC Scopus subject areas
- Reproductive Medicine
- Obstetrics and Gynecology
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Cite this
Tolis, G., Comaru Schally, A. M., Mehta, A. E., & Schally, A. V. (1981). Failure to interrupt established pregnancy in humans by D-tryptophan-6-luteinizing hormone-releasing hormone. Fertility and Sterility, 36(2), 241-242. https://doi.org/10.1016/S0015-0282(16)45688-8