Failure to interrupt established pregnancy in humans by D-tryptophan-6-luteinizing hormone-releasing hormone

G. Tolis, A. M. Comaru Schally, A. E. Mehta, A. V. Schally

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

Four women 5 to 8 weeks into pregnancy, scheduled for therapeutic abortions, were given an analog of gonadotropin-releasing hormone, D-tryptophan-6-LHRH, in an effort to interrupt pregnancy. The treatment consisted of 100 μg injections, given twice daily for 5 to 10 days. No decline in serum β-hCG or progesterone was noted, and menstrual extraction was needed in all women for pregnancy interruption. These data indicate that D-Trp-6-LHRH is not effective as an abortifacient in established pregnancy.

Original languageEnglish (US)
Pages (from-to)241-242
Number of pages2
JournalFertility and Sterility
Volume36
Issue number2
DOIs
StatePublished - Jan 1 1981
Externally publishedYes

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

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