Failure to detect binding of LcrH to the V antigen of Yersinia pestis

K. A. Fields, A. W. Williams, S. C. Straley

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11 Scopus citations

Abstract

V antigen of Yersinia pestis has been reported to bind the chaperone LcrH. We were unable to demonstrate this interaction. Despite methodological differences between our study and an earlier study we believe that the previous findings were artifactual. One likely confounding element was the tendency of LcrH to adhere on its own to metal chelation chromatographic resin.

Original languageEnglish (US)
Pages (from-to)3954-3957
Number of pages4
JournalInfection and Immunity
Volume65
Issue number9
StatePublished - Oct 1 1997

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ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

Cite this

Fields, K. A., Williams, A. W., & Straley, S. C. (1997). Failure to detect binding of LcrH to the V antigen of Yersinia pestis. Infection and Immunity, 65(9), 3954-3957.