TY - JOUR
T1 - Factors predicting work outcome in Japanese patients with schizophrenia
T2 - Role of multiple functioning levels
AU - Sumiyoshi, Chika
AU - Harvey, Philip D.
AU - Takaki, Manabu
AU - Okahisa, Yuko
AU - Sato, Taku
AU - Sora, Ichiro
AU - Nuechterlein, Keith H.
AU - Subotnik, Kenneth L.
AU - Sumiyoshi, Tomiki
N1 - Funding Information:
This work was supported by Japan Society for the Promotion of Science (JSPS) Grant-in-Aid for Scientific Research (C) No. 22530691 to CS and No. 26461761 to TS 7 , as well as Health and Labour Sciences Research Grants for Comprehensive Research on Disability, Health, and Welfare ( H24-Seishin-Ippan-002 and H26-Seishin-Ippan-011 ) and Intramural Research Grant for Neurological and Psychiatric Disorders of NCNP ( 21-1 ) and (27-1) to TS 7 .
Publisher Copyright:
© 2015 The Authors.
PY - 2015/9/1
Y1 - 2015/9/1
N2 - Functional outcomes in individuals with schizophrenia suggest recovery of cognitive, everyday, and social functioning. Specifically improvement of work status is considered to be most important for their independent living and self-efficacy. The main purposes of the present study were 1) to identify which outcome factors predict occupational functioning, quantified as work hours, and 2) to provide cut-offs on the scales for those factors to attain better work status. Forty-five Japanese patients with schizophrenia and 111 healthy controls entered the study. Cognition, capacity for everyday activities, and social functioning were assessed by the Japanese versions of the MATRICS Cognitive Consensus Battery (MCCB), the UCSD Performance-based Skills Assessment-Brief (UPSA-B), and the Social Functioning Scale Individuals' version modified for the MATRICS-PASS (Modified SFS for PASS), respectively. Potential factors for work outcome were estimated by multiple linear regression analyses (predicting work hours directly) and a multiple logistic regression analyses (predicting dichotomized work status based on work hours). ROC curve analyses were performed to determine cut-off points for differentiating between the better- and poor work status. The results showed that a cognitive component, comprising visual/verbal learning and emotional management, and a social functioning component, comprising independent living and vocational functioning, were potential factors for predicting work hours/status. Cut-off points obtained in ROC analyses indicated that 60-70% achievements on the measures of those factors were expected to maintain the better work status. Our findings suggest that improvement on specific aspects of cognitive and social functioning are important for work outcome in patients with schizophrenia.
AB - Functional outcomes in individuals with schizophrenia suggest recovery of cognitive, everyday, and social functioning. Specifically improvement of work status is considered to be most important for their independent living and self-efficacy. The main purposes of the present study were 1) to identify which outcome factors predict occupational functioning, quantified as work hours, and 2) to provide cut-offs on the scales for those factors to attain better work status. Forty-five Japanese patients with schizophrenia and 111 healthy controls entered the study. Cognition, capacity for everyday activities, and social functioning were assessed by the Japanese versions of the MATRICS Cognitive Consensus Battery (MCCB), the UCSD Performance-based Skills Assessment-Brief (UPSA-B), and the Social Functioning Scale Individuals' version modified for the MATRICS-PASS (Modified SFS for PASS), respectively. Potential factors for work outcome were estimated by multiple linear regression analyses (predicting work hours directly) and a multiple logistic regression analyses (predicting dichotomized work status based on work hours). ROC curve analyses were performed to determine cut-off points for differentiating between the better- and poor work status. The results showed that a cognitive component, comprising visual/verbal learning and emotional management, and a social functioning component, comprising independent living and vocational functioning, were potential factors for predicting work hours/status. Cut-off points obtained in ROC analyses indicated that 60-70% achievements on the measures of those factors were expected to maintain the better work status. Our findings suggest that improvement on specific aspects of cognitive and social functioning are important for work outcome in patients with schizophrenia.
KW - Cognition
KW - Everyday-living skills
KW - Functional outcomes
KW - Social functioning
KW - Work outcome
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U2 - 10.1016/j.scog.2015.07.003
DO - 10.1016/j.scog.2015.07.003
M3 - Article
AN - SCOPUS:84942200095
VL - 2
SP - 105
EP - 112
JO - Schizophrenia Research: Cognition
JF - Schizophrenia Research: Cognition
SN - 2215-0013
IS - 3
ER -