Factors associated with reduced visual acuity during long-term follow-up of patients with idiopathic central serous chorioretinopathy

Roy H. Loo, Ingrid U. Scott, Harry W. Flynn, J. Donald M. Gass, Timothy G. Murray, Mary Lou Lewis, Phillip J. Rosenfeld, William E. Smiddy

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233 Scopus citations

Abstract

Purpose: To investigate factors associated with reduced visual acuity during long-term follow-up of patients with idiopathic central serous chorioretinopathy (ICSC). Methods: Retrospective consecutive case series that included patients with ICSC who were younger than 50 years of age at the time of initial examination and were followed up for ≥3 years. Results: The mean follow-up for 101 involved eyes of 61 patients was 9.8 years (median, 8.0 years). Eyes were stratified into two groups based on visual acuity at the final examination: Group 1, visual acuity of 20/40 or better; and Group 2, visual acuity of worse than 20/40. Findings identified as potential risk factors for reduced vision at the final follow-up examinations for Group 1 versus Group 2 included the following: macular retinal pigment epithelium atrophy (90.8% versus 96.0%, respectively; P = 0.68); persistent pigment epithelial detachment or persistent subretinal fluid (5.3% versus 28.0%, respectively; P = 0.004); recurrences (39.5% versus 68.0%, respectively; P = 0.020); laser treatment (28.9% versus 32.0%, respectively; P = 0.80); and submacular choroidal neovascularization (0.0 versus 8.0%, respectively; P = 0.059). Conclusions: Factors associated with reduced visual acuity during long-term follow-up of patients with ICSC included persistent pigment epithelial detachment and/or subretinal fluid, recurrences, and submacular choroidal neovascularization.

Original languageEnglish (US)
Pages (from-to)19-24
Number of pages6
JournalRetina
Volume22
Issue number1
DOIs
StatePublished - Feb 1 2002

Keywords

  • Idiopathic central serous chorioretinopathy (ICSC)

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems

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